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DOI: 10.1055/s-0043-1776263
Hepatic Visceral Larva Migrans: A Case Series
Funding None.
Abstract
Visceral larva migrans is an uncommon systemic parasitic infection of liver caused by second-stage larva of Toxocara canis or Toxocara catis. The liver is the most common visceral organ to be involved. The diagnosis is usually delayed because of a lack of awareness about visceral larva migrans in adults, with most patients confused with either an abscess or neoplastic nodules. Heterogenous solid cystic, multiple hypodense, and hypovascular lesions on imaging with peripheral eosinophilia make the diagnosis in most cases. We present four adult patients with 2 to 4 weeks of fever and very high peripheral eosinophilia. The liver biopsy in three cases revealed an eosinophilic abscess. All cases on treatment with albendazole showed a good response. Visceral larva migrans must be considered in patients with heterogenous, hypovascular space-occupying liver lesions presenting with fever and peripheral eosinophilia.
Keywords
visceral larva migrans - eosinophilia - parasitic infections of the liver - toxocariasis - albendazole - eosinophilic abscessEthical Statement
Ethics Committee of Choithram Hospital & Research Centre approved the submission of this case series for publication.
Data Availability Statement
There is no data associated with this work.
Authors' Contribution
All authors contributed equally to the article.
Publication History
Received: 31 May 2023
Accepted: 07 July 2023
Article published online:
12 October 2023
© 2023. Gastroinstestinal Infection Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Rohilla S, Jain N, Yadav R, Dhaulakhandi DB. Hepatic visceral larva migrans. BMJ Case Rep 2013; 2013: bcr2013009288
- 2 Baever PC, Jung RC, Cupp EW. Clinical parasitology, 9th edn. Philadelphia, PA: Lea & Febiger, 1984: 320-329
- 3 Hombu A, Yoshida A, Kikuchi T, Nagayasu E, Kuroki M, Maruyama H. Treatment of larva migrans syndrome with long-term administration of albendazole. J Microbiol Immunol Infect 2019; 52 (01) 100-105
- 4 Lim JH. Toxocariasis of the liver: visceral larva migrans. Abdom Imaging 2008; 33 (02) 151-156
- 5 Laroia ST, Rastogi A, Sarin SK. Case series of visceral larva migrans in the liver: CT and MRI findings. IJCRI 2012; 3: 7-12
- 6 Bhatia V, Sarin SK. Hepatic visceral larva migrans: evolution of the lesion, diagnosis, and role of high-dose albendazole therapy. Am J Gastroenterol 1994; 89 (04) 624-627