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CC BY 4.0 · Glob Med Genet 2023; 10(04): 311-314
DOI: 10.1055/s-0043-1776985
Original Article

Molecular Mimicry between Meningococcal B Factor H-Binding Protein and Human Proteins

Darja Kanduc 
1   Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy
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Abstract

This study calls attention on molecular mimicry and the consequent autoimmune cross reactivity as the molecular mechanism that can cause adverse events following meningococcal B vaccination and warns against active immunizations based on entire antigen.

Keywords

molecular mimicry - Trumenba vaccine - factor H-binding protein - human proteome - adverse events

Supplementary Material



Publication History

Article published online:
16 November 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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