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CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2023; 10(04): 141-145
DOI: 10.1055/s-0044-1779007
SFM Practice Guidelines

SFM Fetal Therapy Practice Guidelines: Fetal Tissue Biopsy

Aparna K. Sharma 
1   Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
,
Anubhuti Rana
1   Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
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Abstract

Prenatal diagnostic invasive procedures are used to determine if a fetus is at risk of a genetic disease. Analysis based on cells obtained from amniocentesis or chorionic villous sampling is the more commonly performed prenatal diagnostic invasive procedure. For certain indications, however, fetal skin biopsy, muscle biopsy, kidney biopsy, and fetal tissue biopsy of a tumor or mediastinal mass have also been performed. These procedures are rarely indicated in the current scenario when molecular tests are available for most of the genetic conditions. However, there are some genetic conditions for which no specific molecular test is available and prenatal diagnosis can only be done by biopsy of the fetal part during ultrasound guidance.

Keywords

fetal skin biopsy - fetal tissue biopsy - fetus - ultrasound - prenatal


Publication History

Article published online:
15 March 2024

© 2024. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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