Rofo 2024; 196(S 01): S42-S43
DOI: 10.1055/s-0044-1781593
Abstracts
Vortrag (Wissenschaft)
Muskuloskelettale Radiologie

A radiologic evaluation study of bone mineral density between bowel perforation patients and GI healthy controls.

Authors

  • N Abdullayev

    1   GFO Kliniken Troisdorf, Klinik für Radiologie, Neuroradiologie und Nuklearmedizin, Troisdorf

  • S Sanduleanu

    2   Sevagram Care Center, Henri Dunantstraat 3, 6419 PB Heerlen, the Netherlands., Heerlen

  • N Talibova

    3   Department of Internal Medicine III, University Hospital Ulm, Germany, Ulm

  • M Erdogan

    4   Department of Radiology and Neuroradiology, GFO Clinics Troisdorf, Academic Hospital of the Friedrich-Wilhelms-University Bonn, Troisdorf, Germany, Troisdorf

  • J Rahn

    4   Department of Radiology and Neuroradiology, GFO Clinics Troisdorf, Academic Hospital of the Friedrich-Wilhelms-University Bonn, Troisdorf, Germany, Troisdorf

  • J Kottlors

    5   Institute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany, Köln

  • L Görtz

    5   Institute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany, Köln

  • J Bremm

    5   Institute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany, Köln

  • C Bruns

    6   Department of General, Visceral, Tumor and Transplantation Surgery, University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany; Center for Integrated Oncology (CIO) Aachen, Bonn, Cologne and Düsseldorf, Cologne, Germany., Köln

  • D Maintz

    5   Institute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany, Köln

  • K Ersahin

    7   Department of General and Visceral Surgery, GFO Clinics Troisdorf, Academic Hospital of the Friedrich-Wilhelms-University Bonn, Troisdorf, Germany, Troisdorf
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Zielsetzung Anecdotal clinical and physiological evidence exists that osteoporosis may be the initial sign of bowel disease in otherwise asymptomatic elderly patients, often warranting referral to a physician for further evaluation and management. Our hypothesis is that patients with a decreased bone mineral density, and in particular osteoporosis will have a higher risk for gastrointestinal (GI) perforation.

Material und Methoden Contrast-enhanced computed tomography (CECT) scans of 37 consecutive GI perforation patients performed with the same CT scanner were analyzed and compared to 37 patients with comparable demographics. Measurement of BMD without the use of an external reference phantom was performed using a standardized method using an established software (IntelliSpace, Philips, Am-sterdam, The Netherlands) using 3D regions of interests in the bone marrow of the vertebral bodies L1-L3 on CT. Spectrometric calibration of Hounsfield units to the mineral scale was performed with density measurements in the paraver-tebral muscles (erector spinae) and the subcutaneous fat tissue.

Ergebnisse Analysis of the bone mineral density for the two matched groups shows a median density of 135.9 ± 24.3 mg/ml for the control group while the group with GI perforation patients had a significantly lower bone density of 96.9 ± 27.5 mg/ml (p<0.05). The computed bone mineral density T-scores and Z-scores also differed significantly (p<0.05) between the two groups, amounting to -1.6 (+/- 0.83) and 0 (+/- 0.96), respectively, in the control group and -2.9 (+/- 0.90) and -0.8 (+/-0.91), respectively, in the GI perforation group.

Schlussfolgerungen BMD was significantly reduced in GI perforation patients compared to matched GI healthy controls. Despite the commonly described significance of osteopenia in elderly patients undergoing emergency gastrointestinal surgery this study is as far as we can discern one of the first CT imaging studies to compare bone mineral density in GI perforation patients versus healthy controls.



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Artikel online veröffentlicht:
12. April 2024

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