CC BY 4.0 · The Arab Journal of Interventional Radiology 2024; 08(02): 096-099
DOI: 10.1055/s-0044-1782693
Original Article

Antithrombotic Therapy for Inferior Vena Cava Stenting of Malignant Inferior Vena Cava Syndrome: A Questionnaire Study of Japan Interventional Radiology Study Group (JIVROSG)

Mizuki Ozawa
1   Department of Diagnostic Radiology, National Cancer Center Hospital, Tsukiji, Chuo-ku, Tokyo, Japan
Miyuki Sone
1   Department of Diagnostic Radiology, National Cancer Center Hospital, Tsukiji, Chuo-ku, Tokyo, Japan
Shunsuke Sugawara
1   Department of Diagnostic Radiology, National Cancer Center Hospital, Tsukiji, Chuo-ku, Tokyo, Japan
Yasuaki Arai
1   Department of Diagnostic Radiology, National Cancer Center Hospital, Tsukiji, Chuo-ku, Tokyo, Japan
Masahiko Kusumoto
1   Department of Diagnostic Radiology, National Cancer Center Hospital, Tsukiji, Chuo-ku, Tokyo, Japan
› Author Affiliations
Funding This study was funded by the National Cancer Center under the National Cancer Center Research and Development Fund (grant number 2020-J-3). The funding body had no role in the design of the study; collection, analysis, or interpretation of data; or in writing the manuscript.


Purpose The aim of this study was to evaluate the differences in antithrombotic therapy policies for inferior vena cava (IVC) stent placement among institutions and interventional radiologists in Japan.

Materials and Methods The cross-sectional online-based questionnaire was conducted between December 2022 and January 2023, and a total of 114 institutions were included in this study. The questionnaire contained eight questions that were grouped into three sections: (1) whether IVC stents have been performed or not, (2) the number of IVC stent placements, and (3) the basic strategy of antithrombotic therapy for pre-, intra-, and post-IVC stent placement.

Results Of the 114 institutions, 38 responses (33%) were collected. Twenty-four of the 38 institutions (63%) had performed IVC stent placement during the study period. The mean number of IVC stent placements during the study period was 3.4 cases per institution. The most frequently selected antithrombotic therapeutic strategies pre-, intra-, and post-stenting were no antithrombotic therapy (62.5%), anticoagulation therapy (54.2%), and no antithrombotic therapy (41.7%).

Conclusion This study has revealed there is no consensus regarding antithrombotic therapy for IVC stent placement in Japan. The results of this study may contribute to our understanding of the status of antithrombotic therapy for IVC stent placement. Future prospective studies are warranted to clarify the periprocedural antithrombotic therapy for IVC stent placement.

Ethical Approval Statement

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required. This retrospective study was approved by the Institutional Ethics Committee (approval number: NCCH-2018–049).

Data Availability Statement

All the data published within this article will be made available by the corresponding author, upon reasonable request. We take full responsibility for the data, analyses, interpretation, and research conduct. We have full access to all data and have obtained the rights to publish these results.

Authors' Contribution

All authors made substantial contributions to the study concept or the data analysis or interpretation, drafted the manuscript or revised it critically for important intellectual content, approved the final version of the manuscript to be published, and agreed to be accountable for all aspects of the work.

Publication History

Article published online:
19 April 2024

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