RSS-Feed abonnieren

DOI: 10.1055/s-0044-1788998
Imaging in Neurotuberculosis
Authors

Abstract
Central nervous system tuberculosis can occur in various forms and carries high morbidity despite anti-tubercular treatment. Accurate and early diagnosis based on imaging can help improve prognosis and prevent complications. Confirmation of tubercular bacteria in CSF culture methods, and molecular analysis poses challenges due to invasive and time-consuming procedures. Advanced neuroimaging techniques are greatly helpful in making presumptive diagnoses. Here we described imaging features of multiple forms of CNS tuberculosis with advanced neuroimaging. This paper will help neuroradiologists to identify CNS TB and related imaging features.
Ethical Approval
This work has been approved by the Institute Ethical Committee (IEC).
Authors' Contributions
S.A., S.A.S., E.S., and B.D.C. contributed to the acquisition, analysis, conception, design, and drafting of the work. S.A., S.A.S., E.S., along with A.G. contributed to the final draft, revisions, upload, and submission of the final revised work. All authors have agreed both to be personally accountable for own contributions and ensured that questions related to the accuracy or integrity of any part of the work, even ones in which one was not personally involved, are appropriately investigated, resolved, and the resolution documented in the literature.
Publikationsverlauf
Artikel online veröffentlicht:
14. August 2024
© 2024. Indographics. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Cherian A, Ajitha KC, Iype T, Divya KP. Neurotuberculosis: an update. Acta Neurol Belg 2021; 121 (01) 11-21
- 2 Jamoussi M, Benrhouma H, Miladi Z. et al. Pediatric neurotuberculosis: a cases series and review of the literature. Eur J Paediatr Neurol 2023; 43: 6-11
- 3 Burrill J, Williams CJ, Bain G, Conder G, Hine AL, Misra RR. Tuberculosis: a radiologic review. Radiographics 2007; 27 (05) 1255-1273
- 4 Chin JH. Tuberculous meningitis: diagnostic and therapeutic challenges. Neurol Clin Pract 2014; 4 (03) 199-205
- 5 Imran D, Estiasari R, Maharani K. et al. Presentation, etiology, and outcome of brain infections in an Indonesian hospital: a cohort study. Neurol Clin Pract 2018; 8 (05) 379-388
- 6 Katrak SM, Shembalkar PK, Bijwe SR, Bhandarkar LD. The clinical, radiological and pathological profile of tuberculous meningitis in patients with and without human immunodeficiency virus infection. J Neurol Sci 2000; 181 (1-2): 118-126
- 7 Schaller MA, Wicke F, Foerch C, Weidauer S. central nervous system tuberculosis : etiology, clinical manifestations and neuroradiological features. Clin Neuroradiol 2019; 29 (01) 3-18
- 8 Zunt JR. Tuberculosis of the central nervous system. Continuum (Minneap Minn) 2018; 24 (5, Neuroinfectious Disease): 1422-1438
- 9 Synmon B, Das M, Kayal AK. et al. Clinical and radiological spectrum of intracranial tuberculosis: a hospital based study in Northeast India. Indian J Tuberc 2017; 64 (02) 109-118
- 10 Dastur DK, Manghani DK, Udani PM. Pathology and pathogenetic mechanisms in neurotuberculosis. Radiol Clin North Am 1995; 33 (04) 733-752
- 11 Jamieson DH. Imaging intracranial tuberculosis in childhood. Pediatr Radiol 1995; 25 (03) 165-170
- 12 Bernaerts A, Vanhoenacker FM, Parizel PM. et al. Tuberculosis of the central nervous system: overview of neuroradiological findings. Eur Radiol 2003; 13 (08) 1876-1890
- 13 Mezochow A, Thakur K, Vinnard C. Tuberculous meningitis in children and adults: new insights for an ancient foe. Curr Neurol Neurosci Rep 2017; 17 (11) 85
- 14 Splendiani A, Puglielli E, De Amicis R, Necozione S, Masciocchi C, Gallucci M. Contrast-enhanced FLAIR in the early diagnosis of infectious meningitis. Neuroradiology 2005; 47 (08) 591-598
- 15 Nogami K, Nomura S, Kashiwagi S, Kato S, Yamashita K, Ito H. Fluid-attenuated inversion-recovery imaging of cerebral infarction associated with tuberculous meningitis. Comput Med Imaging Graph 2000; 24 (05) 333-337
- 16 Tai MS, Viswanathan S, Rahmat K. et al. Cerebral infarction pattern in tuberculous meningitis. Sci Rep 2016; 6: 38802
- 17 Baloji A, Ghasi RG. MRI in intracranial tuberculosis: have we seen it all?. Clin Imaging 2020; 68: 263-277
- 18 Marais S, Scholtz P, Pepper DJ, Meintjes G, Wilkinson RJ, Candy S. Neuroradiological features of the tuberculosis-associated immune reconstitution inflammatory syndrome. Int J Tuberc Lung Dis 2010; 14 (02) 188-196
- 19 Patkar D, Narang J, Yanamandala R, Lawande M, Shah GV. Central nervous system tuberculosis: pathophysiology and imaging findings. Neuroimaging Clin N Am 2012; 22 (04) 677-705
- 20 Goyal M, Sharma A, Mishra NK, Gaikwad SB, Sharma MC. Imaging appearance of pachymeningeal tuberculosis. AJR Am J Roentgenol 1997; 169 (05) 1421-1424
- 21 Chotmongkol V, Khamsai S. Diffuse hypertrophic pachymeningeal tuberculosis. Tuberc Respir Dis (Seoul) 2020; 83 (04) 321-323
- 22 Whiteman M, Espinoza L, Post MJ, Bell MD, Falcone S. Central nervous system tuberculosis in HIV-infected patients: clinical and radiographic findings. AJNR Am J Neuroradiol 1995; 16 (06) 1319-1327
- 23 Kim HJ, Shim KW, Lee MK. et al. Tuberculous encephalopathy without meningitis: pathology and brain MRI findings. Eur Neurol 2011; 65 (03) 156-159
- 24 Rajeswari R, Balasubramanian R, Venkatesan P. et al. Short-course chemotherapy in the treatment of Pott's paraplegia: report on five year follow-up. Int J Tuberc Lung Dis 1997; 1 (02) 152-158
- 25 Saidane O, Sellami M, Cheikhrouhou S. et al. Clinical features and prognosis factors of spinal tuberculosis in Northern Tunisia: a case series of 60 patients [in French]. Bull Soc Pathol Exot 2019; 112 (02) 71-78
- 26 Rodriguez-Takeuchi SY, Renjifo ME, Medina FJ. Extrapulmonary tuberculosis: pathophysiology and imaging findings. Radiographics 2019; 39 (07) 2023-2037
- 27 Gupta RK, Gupta S, Kumar S, Kohli A, Misra UK, Gujral RB. MRI in intraspinal tuberculosis. Neuroradiology 1994; 36 (01) 39-43
- 28 Sahu SK, Giri S, Gupta N. Longitudinal extensive transverse myelitis due to tuberculosis: a report of four cases. J Postgrad Med 2014; 60 (04) 409-412
- 29 Nair AP, Mehrotra A, Das KK. et al. Calvarial tuberculosis of the parietal bone: a rare complication after dental extraction. Asian J Neurosurg 2015; 10 (03) 219-221
- 30 Vu K, Adler H, Gibbons E, Pearson J, Betz W. Intracerebral tuberculomas: a rare cause of seizure in an immunocompetent young male. IDCases 2019; 18: e00599
- 31 Geri G, Passeron A, Heym B. et al. Paradoxical reactions during treatment of tuberculosis with extrapulmonary manifestations in HIV-negative patients. Infection 2013; 41 (02) 537-543
- 32 Cheng VC, Yam WC, Woo PC. et al. Risk factors for development of paradoxical response during antituberculosis therapy in HIV-negative patients. Eur J Clin Microbiol Infect Dis 2003; 22 (10) 597-602
- 33 Meintjes G, Lawn SD, Scano F. et al; International Network for the Study of HIV-associated IRIS. Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings. Lancet Infect Dis 2008; 8 (08) 516-523
- 34
Lehman VT,
Brinjikji W,
Kallmes DF.
et al.
Clinical interpretation of high-resolution vessel wall MRI of intracranial arterial
diseases. Br J Radiol 2016; 89 (1067) 20160496
Reference Ris Wihthout Link
- 35 Pretell EJ, Martinot Jr C, Garcia HH, Alvarado M, Bustos JA, Martinot C. Cysticercosis Working Group in Peru. Differential diagnosis between cerebral tuberculosis and neurocysticercosis by magnetic resonance spectroscopy. J Comput Assist Tomogr 2005; 29 (01) 112-114
- 36 Margariti P, Sanchez-Montanez A, Delgado I, Elorza Alvarez I, Vazquez E. At-risk brain tissue identified with arterial spin labeling in neurotuberculosis. Pediatr Radiol 2013; 43 (08) 1049-1052
- 37 Kulanthaivelu K, Jabeen S, Saini J. et al. Amide proton transfer imaging for differentiation of tuberculomas from high-grade gliomas: preliminary experience. Neuroradiol J 2021; 34 (05) 440-448
- 38 Awada A, Daif AK, Pirani M, Khan MY, Memish Z, Al Rajeh S. Evolution of brain tuberculomas under standard antituberculous treatment. J Neurol Sci 1998; 156 (01) 47-52