EVALUATION OF SELF-REFERRED QUALITY OF LIFE BEFORE THE TREATMENT IN PATIENTS WITH COLORECTAL ADENOCARCINOMA IN A CITY FROM WESTERN SANTA CATARINA: PRELIMINARY RESULTS

Introduction: Colorectal cancer (CRC) is defined as malignant neoplasms localized at the colon, rectum and large intestine. It is the third most frequent cancer in the world and the second in number of deaths. Objective: To analyze quality of life parameters in patients diagnosed with adenocarcinoma histologic subtype of CRC. Methods: selection of participants with adenocarcinoma subtype CRC, without previous treatment for the neoplasia, from 18 to 70 years, with the application of the EORTC QLQ-C30 and EORTC QLQ-CR29 quality of life questionnaires after signature of the Informed Consent Form. The quality of life score is calculated with the Microsoft Excel 2010 software, following scoring procedures of the questionnaires. Results: 14 people preliminarily participated in the study, 7 men and 7 women. The mean (M) of age of the patients is 59 years, standard deviation (SD) is 11,11 years. The 30 questions from the C30 questionnaire were split into 3 scales (functional (FS), symptoms (SS) and global quality of life (QL)), while the 29 questions from the CR29 were split into functional scale (FS) and symptoms scale (SS). The score was calculated and varies from 0 to 100. To FS and QL, the performance of the patient is better if the score is high. About SS, when it gets closer to 0, means that the patient has fewer symptoms from the CRC. The scores were calculated in general form and by sex, M from women (MW) and SD from women (SDW), M from men (MM) and SD from men (SDM). In the C30 questionnaire, for FS, M was 69.83 and SD was 19.36 (MW= 68.24 and SDW=17.43; MM=71.42 and SDM=22.42). For SS, M was 32.73 and SD was 22.43 (MW=29.75 and SDM=18,68). For QL, M was 61.90 and SD was 25.88 (MW=67.85, SDW=21.74; MM=55.94, SDM=29.93). In the CR29 questionnaire, for FS, M was 55.76 and SD was 17.67 (MW=59.93, SDW=6.21; MM=51.59; SDM=17.49). For SS, M was 26.94 and SD=11.66 (MW=20.40, SDW=14.39; MM=33.48, SDM=7.91) Conclusion: For FS, patients in general present values near the reference value, with a small difference between men and women. About SS, some values are close to the reference values, while others present above or below the reference in some categories, showing that some symptoms are more or less referred. Factors like CRC staging, age mean and comorbidities may be responsible for the differences. For QL, the values are close to the reference; however, there is a significant difference between self-perception of health in women and men (smaller for men).

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Artikel online veröffentlicht:
23. Oktober 2019