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DOI: 10.1055/s-0044-1798265
MANAGEMENT OF RENAL CELL CARCINOMA LOCAL RELAPSE: EXCLUSIVE HYPOFRACTIONATED RADIOTHERAPY IN ELDERLY PATIENT
Authors
Case presentation: Elderly patient, 93 years old, diagnosed with clear cell renal carcinoma, who underwent right renal nephrectomy in 2012, at an early stage. In 2014, he had a local relapse and was treated with three-dimensional conformal external radiotherapy, total prescribed dose of 35Gy in 5 fractions. There was complete disappearance of the lesion after 3 years. Patient remains asymptomatic and has no signs of sequelae. Discussion: Clear cell renal carcinoma is the most common variant of renal tumors and is historically considered a radioresistant tumor. About 40% of patients die due to the progression of this disease, making this tumor the most lethal urological malignant lesion. The most common metastases are lungs and bones, and relapse event after radical nephrectomy is a rare event, occurring in less than 2% of cases. However, with the emergence of hypofractionation, high doses performed in small volumes of treatment, allowed a better management of the tumor, thus bringing better Results: final comments Local relapse of clear cell carcinoma is a rare event. In this case, surgical treatment and chemotherapy were refused by patient and family members. Hypofractionated radiotherapy was considered as an alternative and has an excellent response. It was a safe approach and provided effective local control.
Publication History
Article published online:
23 October 2019
© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
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PRISCILLA FURTADO SOUZA PASQUINELLI, LITMANNE REZENDE BRANDAO, AMANDA MUNIZ FONTES, CAIO GONÇALVES GOMES, BRUNO LUIZ SALES, EDSON RAIMUNDO VILAS BOAS JUNIOR, LIVIA CAMARGOS CRUZ, PERICLES CRISOSTOMO DE SOUSA, DANIELA DE SOUZA DA MOTA E CAMANDUCAIA, KAMILA SILVA ALFRADIQUE TOUÇA, FLAVIA CRISTINA DE CASTRO, GEOVANNA CRISTINY BARBOSA, LUDMYLLA GEIZELLER RODRIGUES NOVATO, ELISA KEIKO DE SOUZA IGARASHI. MANAGEMENT OF RENAL CELL CARCINOMA LOCAL RELAPSE: EXCLUSIVE HYPOFRACTIONATED RADIOTHERAPY IN ELDERLY PATIENT. Brazilian Journal of Oncology 2019; 15.
DOI: 10.1055/s-0044-1798265