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CC BY 4.0 · Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Surgery 2024; 39(04): s00451801857
DOI: 10.1055/s-0045-1801857
Artigo Original

Tranexamic Acid in the Incidence of Hematoma in Breast Explantation Surgery

Article in several languages: português | English
Ricardo Eustachio de Miranda 
1   Consultório particular, cirurgia plástica, São Paulo, SP, Brasil
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Funding The author declares that he received no funding for this research. Ensaios Clínicos Não. | Clinical Trials None.
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Abstract

Introduction Surgical procedures are subject to several postoperative complications and hematoma is a frequent occurrence. Surgeries involving wide dissection, such as total intact capsulectomies, are more prone to bleeding. Several medications have been used to reduce hematomas, such as tranexamic acid. No articles in the medical literature analyze the relationship between tranexamic acid and the incidence of hematomas in total intact capsulectomy surgeries.

Methods This study collected retrospective medical record data to determine the incidence of hematoma in total intact capsulectomy surgeries in two groups of patients. Patients underwent total intact capsulectomy with or without mastopexy and there was no insertion of a new breast implant. A group of 140 patients received intravenous and topical tranexamic acid during surgery and another group of 140 patients did not. Surgeries occurred from January 2022 to December 2023 and data subsequently underwent statistical analysis.

Results The two groups were comparable and presented normal distribution. Tranexamic acid statistically reduced the incidence of hematoma (p value = 0.004). Implant size was also statistically significant in decreasing hematoma incidence, with a mean volume of 350 mL in cases with hematoma and 291 mL in the group without hematoma (p value = 0.020). The remaining variables presented p values <0.05.

Conclusion Topical and intravenous use of tranexamic acid reduces the incidence of hematoma after intact total capsulectomy in patients with breast implants.

Keywords

breast - mammaplasty - breast implants - postoperative complications - hematoma

Author's Contribution

RED: data analysis, interpretation, or both, statistical analysis, final manuscript approval, funding acquisition, data collection, conceptualization, study conception and design, resource management, project management, investigation, methodology, surgery, experiment, or both performance, writing - original draft preparation, review, and editing, supervision, validation, and visualization.




Publication History

Received: 02 March 2024

Accepted: 29 September 2024

Article published online:
10 February 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Ricardo Eustachio de Miranda. Ácido tranexâmico na incidência de hematoma na cirurgia de explante mamário. Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Surgery 2024; 39: s00451801857.
DOI: 10.1055/s-0045-1801857