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CC BY-NC-ND 4.0 · International Journal of Epilepsy 2025; 11(01): 040-042
DOI: 10.1055/s-0045-1802632
EEG of the Month

SeLECTS—Self-Limiting Epilepsy with Centrotemporal Spikes: Presence of ESES Correlates with Neuropsychological Regression

Harish Jayakumar 
1   Department of Neurology, JK Comprehensive Epilepsy Centre, JK Institute of Neurology, Madurai, Tamil Nadu, India
,
Rama Shankari Padmanabhan
2   Department of Neuroanesthesiology, JK Institute of Neurology, Madurai, Tamil Nadu, India
,
Jayakumar Vaikundam
3   Department of Neurosciences, JK Institute of Neurology, Madurai, Tamil Nadu, India
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Abstract

We present a developmentally normal 8-year-old male child with infrequent nocturnal focal seizures since 6 years of age. Since the onset of seizures, he has been having poor academic performance with difficulty in learning and preserved language. Electroencephalogram (EEG) showed a normal background and frequent bisynchronous biphasic centro-parieto-temporal large amplitude spikes with maximum negativity over the left temporal region. His sleep record showed continuous runs of large amplitude generalized spikes with maximum negativity over the centrotemporal region and spike-wave index > 90. There is a clear correlation between the presence of electrical status epilepticus during sleep (ESES) and neuropsychological deficits. EEG is resistant to antiseizure medications, and these findings disappear before mid to late adolescence, and deficits recede with the remission of ESES.

Keywords

BECTS - SeLECTS - CSWS - ESES - benign epilepsy with centrotemporal spikes


Publication History

Article published online:
12 February 2025

© 2025. Indian Epilepsy Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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