Subscribe to RSS
Download PDF
DOI: 10.1055/s-0045-1805005
Overcoming Complexity: Percutaneous Embolization for Hepatic Artery Pseudoaneurysms in Hereditary Hemorrhagic Telangiectasia (HHT)
Authors
Funding None.
Abstract
Osler-Weber-Rendu syndrome also known as hereditary hemorrhagic telangiectasia (HHT) is a rare vascular dysplasia affecting multiple organ systems in the body. Hepatic manifestations of HHT include telangiectasias, large confluent masses, hepatic perfusion abnormalities, and various types of intrahepatic vascular shunts. Spontaneous hepatic pseudoaneurysm (PA) in HHT is a less well-known phenomenon, with fewer than 20 cases reported in the literature so far. Even rarer is the use of percutaneous glue (N-butyl cyanoacrylate) embolization to manage multiple hepatic PAs in HHT syndrome. The purpose of this case report is to describe the successful management of multiple hepatic PAs by percutaneous embolization in a 56-year-old male diagnosed with HHT.
Publication History
Article published online:
27 March 2025
© 2025. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Tortora A, Riccioni ME, Gaetani E, Ojetti V, Holleran G, Gasbarrini A. Rendu-Osler-Weber disease: a gastroenterologist's perspective. Orphanet J Rare Dis 2019; 14 (01) 130
- 2 Peinado Cebrián FJ, Estebanez Seco S, Flores-Herrero A. et al. Giant symptomatic aneurysm secondary to hereditary hemorrhagic telangiectasia of a main hepatic artery with aberrant origin in superior mesenteric artery. Ann Vasc Surg 2017; 44: 417.e5-417.e9
- 3 Le TD, Nguyen MD, Than VS. Transhepatic glue injection for hepatic pseudoaneurysm and arteriohepatic venous fistula after the failure of transarterial embolization. International Journal of Gastrointestinal Intervention. 2022; 11 (01) 35-38
- 4 Leitão P, Carvalho A, Guerra C, Gonçalves J, Ramos I. Congestive cirrhosis in Osler-Weber-Rendu syndrome: a rare case report. Radiol Case Rep 2017; 13 (01) 51-54
- 5 Siddiki H, Doherty MG, Fletcher JG. et al. Abdominal findings in hereditary hemorrhagic telangiectasia: pictorial essay on 2D and 3D findings with isotropic multiphase CT. Radiographics 2008; 28 (01) 171-184
- 6 Szmygin M, Szmygin P, Drelich K, Pustelniak O, Pech M, Jargiełło T. The role of interventional radiology in treatment of patients with hereditary hemorrhagic telangiectasia. Eur J Radiol 2023; 162: 110769
- 7 Miyabe K, Akita S, Kitajima Y. et al. Rupture of hepatic aneurysm complicating hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) for which hepatic arterial coil embolization was effective. J Gastroenterol Hepatol 2007; 22 (12) 2352-2357
- 8 Çildağ MB, Gök M, Öztürk T, Köseoğlu ÖFK. Endovascular treatment of a giant aneurysm of the aberrant right hepatic artery in a patient with Osler-Weber-Rendu syndrome: a case report. Vasc Spec Int 2023; 39: 25
- 9 Mittal R, Stephen E, Keshava SN, Moses V, Agarwal S. Percutaneous cyanoacrylate glue embolization for peripheral pseudoaneurysms: an alternative treatment. Indian J Surg 2012; 74 (06) 483-485
- 10 Schutyser W, Budts W, Verhamme P. Percutaneous embolization of pulmonary arteriovenous malformations in adult patient with Rendu-Osler-Weber: a case report. Eur Heart J Case Rep 2023; 7 (11) ytad533
- 11 Chowdhry SA, Ponsky DC, Hsu DP. Treatment of a nasal vascular malformation in a patient with Osler-Weber-Rendu syndrome via percutaneous N-butyl 2-cyanoacrylate embolization: case report and review of the literature. J Otolaryngol Head Neck Surg 2011; 40 (02) E11-E14