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CC BY-NC-ND 4.0 · Sleep Sci
DOI: 10.1055/s-0045-1809061
Original Article

Sleep Architecture, Muscle Function, and Daily Life Activities in Patients with Sarcopenia

Eduardo López-Ramírez
1   Clinic of Sleep Disorders, Faculty of Medicine, Universidad Nacional de México (UNAM), Ciudad de México, Mexico
2   Department of Geriatrics, Hospital General de Zona 76, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, Mexico
,
Gabriela Millán-Rosas
1   Clinic of Sleep Disorders, Faculty of Medicine, Universidad Nacional de México (UNAM), Ciudad de México, Mexico
,
Rafael Santana-Miranda
1   Clinic of Sleep Disorders, Faculty of Medicine, Universidad Nacional de México (UNAM), Ciudad de México, Mexico
,
Daniel Santana-Vargas
1   Clinic of Sleep Disorders, Faculty of Medicine, Universidad Nacional de México (UNAM), Ciudad de México, Mexico
,
Adrián Poblano 
1   Clinic of Sleep Disorders, Faculty of Medicine, Universidad Nacional de México (UNAM), Ciudad de México, Mexico
3   Laboratory of Cognitive Neurophysiology, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INR), Ciudad de México, Mexico
,
Romel Gutiérrez-Escobar
1   Clinic of Sleep Disorders, Faculty of Medicine, Universidad Nacional de México (UNAM), Ciudad de México, Mexico
› Author Affiliations
Funding Source The authors declare that he did not receive financial support from agencies in the public, private, or non-profit sectors to conduct the present study.
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Abstract

Objective

To examine associations between polysomnography, muscle mass and strength, and daily life activity index (DLAI) in patients with sarcopenia.

Materials and Methods

We measured polysomnography, muscle mass and strength, and DLAI in 16 patients with sarcopenia and 26 controls > 60 years old and then compared variables and correlations in the patients with sarcopenia.

Results

We found no differences in polysomnography between patients with sarcopenia and controls. Among patients with sarcopenia, latency to rapid eye-movement (REM) sleep was positively correlated with weight, REM %, and total sleep time was positively correlated with grip strength. Latency of REM sleep was negatively correlated with body mass index, NREM sleep, and apnea index was negatively correlated with grip strength. Daily life activity index correlated positively with grip strength.

Conclusion

Patients with sarcopenia showed significant correlations between polysomnography and weight, body mass index, and grip strength, suggesting a complex relationship involving sleep architecture, muscle function, and DLAI that deserves more research.

Keywords

sarcopenia - polysomnography - muscle mass - grip strength - daily life activities index

Authors' Contributions

ELR: study conception and design, data collection and analysis. GMR, RSM, DSV, AP, and RGE: study design and analysis. All authors wrote and approved the final version of the manuscript.




Publication History

Received: 17 September 2024

Accepted: 07 March 2025

Article published online:
08 July 2025

© 2025. Brazilian Sleep Academy. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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