Abstract
Network pharmacology has emerged as a transformative approach in medical research,
providing a comprehensive perspective on disease complexity and treatment modalities.
This interdisciplinary methodology integrates principles from pharmacology, bioinformatics,
and systems biology to explore the interconnected relationships within biological
networks. Recently, network pharmacology has found application in homeopathic research,
offering a unique framework to decipher the molecular mechanisms underlying the effects
of homeopathic remedies. This article elucidates the principles of network pharmacology,
emphasizing a systems-level understanding of biological networks. A case study explores
the network pharmacology of Arnica montana, a commonly used homeopathic remedy, demonstrating the methodology's potential in
solving the holistic interactions between bioactive compounds and biological systems.
Challenges and future perspectives in homeopathic research are discussed, highlighting
the promise of network pharmacology in enhancing our understanding of homeopathic
remedies, guiding personalized treatment strategies, and integrating homeopathy into
mainstream health care. The application of network pharmacology in homeopathic research
is detailed through diverse approaches, including identifying molecular targets, multitarget
analysis, disease network exploration, and validation of potentization. The integration
of network pharmacology into homeopathic research represents a promising frontier
for understanding and validating the principles of homeopathy, contributing to improved
treatment strategies and patient outcomes.
Keywords
Arnica montana
- homeopathy - network pharmacology
