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CC BY 4.0 · World J Nucl Med
DOI: 10.1055/s-0045-1809422
Case Report

Acute and Chronic Presentation of Melioidosis: 18F-FDG PET/CT Case Series

Harini Koorma 
1   Department of Nuclear Medicine and PET-CT, AIG Hospitals, Hyderabad, Telangana, India
,
Mohan Roop Jayanthi
1   Department of Nuclear Medicine and PET-CT, AIG Hospitals, Hyderabad, Telangana, India
,
Haripriya Reddy Challa
1   Department of Nuclear Medicine and PET-CT, AIG Hospitals, Hyderabad, Telangana, India
,
Nagamani Chella
2   Department of Infectious Diseases, AIG Hospitals, Hyderabad, Telangana, India
,
Suneetha Batchu
3   Department of Microbiology, AIG Hospitals, Hyderabad, Telangana, India
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Abstract

Melioidosis is an infectious disease that is caused by a gram-negative bacillus, Burkholderia pseudomallei, which has been designated as a category B bioterrorism agent by the U.S. Centers for Disease Control and Prevention. Melioidosis manifests as a multi-system disorder. The effectiveness of 18F-FDG PET/CT (18-fluorine-fluorodeoxyglucose positron emission tomography–computed tomography) in diagnosing or managing melioidosis is currently uncertain or not well-established. 18F-FDG PET/CT is a useful tool in detecting the location and extent of abscess formation, assessing the organs involved, and detecting occult foci of infection, due to the multifocal nature of the disease. Herein, we present cases of two patients referred for a whole-body 18F-FDG PET/CT scan with a history of pyrexia of unknown origin.

Keywords

melioidosis - Burkholderia pseudomallei - 18-fluorine-fluorodeoxyglucose positron emission tomography–computed tomography - culture and sensitivity - pyrexia of unknown origin


Publication History

Article published online:
03 June 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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