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DOI: 10.1055/s-0045-1809882
Supera cognitive stimulation study with cognitively-unimpaired older adults: methodology and initial results of a randomized controlled clinical trial
Funding The authors declare that the present study was funded by Supera Instituto de Educação.

Abstract
Scientific investigations have highlighted the benefits of cognitive stimulation for cognitive, psychological, and social aspects in older individuals. However, there is a dearth of long-term, methodologically-rigorous studies. The aim of the present study was to describe the methods and the initial characteristics of the participants in a randomized controlled trial on cognitive stimulation. A total of 578 older individuals accepted invitations to participate in the study. Of these respondents, 362 met the eligibility criteria, and 255 were selected and randomized into the training, active control, and passive control groups. During the baseline stage (T0), 48 participants withdrew, resulting in a final T0 sample of 207 participants. The three groups were similar in terms of cognitive performance and sociodemographic and psychosocial variables, but they differed significantly regarding depressive symptoms, with the training group scoring higher. The methods herein described can help guide future research on cognitive stimulation in older adults.
Authors' Contributions
Conceptualization: TBLS, SMDB, MSY; Data curation: TNO; Investigation: TBLS, TNO, GDS, LAC, APBM, DSB; Methodology: TBLS, APBM, SMDB, MSY; Writing – original draft: TBLS, TNO, GDS, LAC, APBM; Writing – review & editing: TBLS, TNO, GDS, APBM, DSB, MAAS, SAS, SMDB, MSY.
Data Availability Statement
Data is available on demand.
Editor-in-Chief: Hélio A. G. Teive (https://orcid.org/0000-0003-2305-1073).
Associate Editor: Leonardo Cruz de Souza (https://orcid.org/0000-0001-5027-9722).
Publikationsverlauf
Eingereicht: 11. Oktober 2024
Angenommen: 28. April 2025
Artikel online veröffentlicht:
02. Juli 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua Rego Freitas, 175, loja 1, República, São Paulo, SP, CEP 01220-010, Brazil
Thais Bento Lima da Silva, Tiago Nascimento Ordonez, Gabriela dos Santos, Laydiane Alves Costa, Ana Paula Bagli Moreira, Diana dos Santos Bacelar, Maria Antonia Antunes de Souza, Sabrina Aparecida da Silva, Sonia Maria Dozzi Brucki, Monica Sanches Yassuda. Supera cognitive stimulation study with cognitively-unimpaired older adults: methodology and initial results of a randomized controlled clinical trial. Arq Neuropsiquiatr 2025; 83: s00451809882.
DOI: 10.1055/s-0045-1809882
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References
- 1 Bonfanti L, Charvet CJ. Brain Plasticity in Humans and Model Systems: Advances, Challenges, and Future Directions. Int J Mol Sci 2021; 22 (17) 9358
- 2 Gavelin HM, Lampit A, Hallock H, Sabatés J, Bahar-Fuchs A. Cognition-Oriented Treatments for Older Adults: a Systematic Overview of Systematic Reviews. Neuropsychol Rev 2020; 30 (02) 167-193
- 3 Webb SL, Birney DP, Loh V, Walker S, Lampit A, Bahar-Fuchs A. Cognition-oriented treatments for older adults: A systematic review of the influence of depression and self-efficacy individual differences factors. Neuropsychol Rehabil 2022; 32 (06) 1193-1229
- 4 Gómez-Soria I, Iguacel I, Aguilar-Latorre A, Peralta-Marrupe P, Latorre E, Zaldívar JNC, Calatayud E. Cognitive stimulation and cognitive results in older adults: A systematic review and meta-analysis. Arch Gerontol Geriatr 2023; 104: 104807
- 5 Gómez-Soria I, Iguacel I, Cuenca-Zaldívar JN, Aguilar-Latorre A, Peralta-Marrupe P, Latorre E, Calatayud E. Cognitive stimulation and psychosocial results in older adults: A systematic review and meta-analysis. Arch Gerontol Geriatr 2023; 115: 105114
- 6 Calatayud E, Gómez-Cabello A, Gómez-Soria I. Análisis del efecto de un programa de estimulación cognitiva en adultos mayores con cognición normal: ensayo clínico aleatorizado. An Sist Sanit Navar 2021; 44 (03) 361-372
- 7 Gomes ECC, Souza SL, Marques APO, Leal MCC. Treino de estimulação de memória e a funcionalidade do idoso sem comprometimento cognitivo: uma revisão integrativa. Cien Saude Colet 2020; 25 (06) 2193-2202
- 8 Gómez-Soria I, Cuenca-Zaldívar JN, Rodríguez-Roca B, Subirón-Valera AB, Salavera C, Marcén-Román Y. et al. Cognitive Effects of a Cognitive Stimulation Programme on Trained Domains in Older Adults with Subjective Memory Complaints: Randomised Controlled Trial. Int J Environ Res Public Health 2023; 20 (04) 3636
- 9 Coley N, Giulioli C, Aisen PS, Vellas B, Andrieu S. Randomised controlled trials for the prevention of cognitive decline or dementia: A systematic review. Ageing Res Rev 2022; 82: 101777
- 10 Crivelli L, Calandri IL, Suemoto CK, Salinas RM, Velilla LM, Yassuda MS. et al. Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): Study design and harmonization. Alzheimers Dement 2023; 19 (09) 4046-4060
- 11 Brinke LFT, Best JR, Crockett RA, Liu-Ambrose T. The effects of an 8-week computerized cognitive training program in older adults: a study protocol for a randomized controlled trial. BMC Geriatr 2018; 18 (01) 31
- 12 Kivipelto M, Solomon A, Ahtiluoto S, Ngandu T, Lehtisalo J, Antikainen R. et al. The Finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): study design and progress. Alzheimers Dement 2013; 9 (06) 657-665
- 13 Jobe JB, Smith DM, Ball K, Tennstedt SL, Marsiske M, Willis SL. et al. ACTIVE: a cognitive intervention trial to promote independence in older adults. Control Clin Trials 2001; 22 (04) 453-479
- 14 Zülke A, Luck T, Pabst A, Hoffmann W, Thyrian JR, Gensichen J. et al. AgeWell.de - study protocol of a pragmatic multi-center cluster-randomized controlled prevention trial against cognitive decline in older primary care patients. BMC Geriatr 2019; 19 (01) 203
- 15 Yoon JS, Roque NA, Andringa R, Harrell ER, Lewis KG, Vitale T. et al. Intervention comparative effectiveness for adult cognitive training (ICE-ACT) trial: rationale, design, and baseline characteristics. Contemp Clin Trials 2019; 78: 76-87
- 16 Kang M, Ragan BG, Park JH. Issues in outcomes research: an overview of randomization techniques for clinical trials. J Athl Train 2008; 43 (02) 215-221
- 17 Camozzato AL, Kochhann R, Godinho C, Costa A, Chaves ML. Validation of a telephone screening test for Alzheimer's disease. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2011; 18 (02) 180-194
- 18 Paradela EMP, Lourenço RA, Veras RP. Validação da escala de depressão geriátrica em um ambulatório geral. Rev Saude Publica 2005; 39 (06) 918-923
- 19 Martiny C, Silva ACDO, Nardi AE, Pachana NA. Tradução e adaptação transcultural da versão brasileira do Inventário de Ansiedade Geriátrica (GAI). Arch Clin Psychiatry 2011; 38: 08-12
- 20 Pfeffer RI, Kurosaki TT, Harrah Jr CH, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol 1982; 37 (03) 323-329
- 21 Johnson EE, Hamer R, Nora RM, Tan B, Eisenstein N, Engelhart C. The Lie/Bet Questionnaire for screening pathological gamblers. Psychol Rep 1997; 80 (01) 83-88
- 22 Castells MA, Furlanetto LM. Validity of the CAGE questionnaire for screening alcohol-dependent inpatients on hospital wards. Rev Bras Psiquiatr 2005; 27 (01) 54-57
- 23 Amaral-Carvalho V, Lima-Silva TB, Mariano LI, Souza LCd, Guimarães HC, Bahia VS. et al. Brazilian Version of Addenbrooke's Cognitive Examination-Revised in the Differential Diagnosis of Alzheimer'S Disease and Behavioral Variant Frontotemporal Dementia. Arch Clin Neuropsychol 2022; 37 (02) 437-448
- 24 Flaks MK, Forlenza OV, Pereira FS, Viola LF, Yassuda MS. Short cognitive performance test: diagnostic accuracy and education bias in older Brazilian adults. Arch Clin Neuropsychol 2009; 24 (03) 301-306
- 25 Machado TH, Fichman HC, Santos EL, Carvalho VA, Fialho PP, Koenig AM. et al. Normative data for healthy elderly on the phonemic verbal fluency task - FAS. Dement Neuropsychol 2009; 3 (01) 55-60
- 26 Wechsler D. WAIS-III: Wechsler Adult Intelligence Scale – Third Edition. San Antonio, TX: The Psychological Corporation; 1997
- 27 Nascimento E. Adaptação, validação e normatização do WAIS-III para uma amostra brasileira. In: Wechsler D. WAIS-III: Manual para administração e avaliação. São Paulo: Casa do Psicólogo; 2004
- 28 Wilde NJ, Strauss E, Tulsky DS. Memory span on the Wechsler scales. J Clin Exp Neuropsychol 2004; 26 (04) 539-549
- 29 Lezak MD. Principles of Neuropsychological Assessment. In: Feinberg TE, Farah MJ. editors. Behavioral Neurology and Neuropsychology. New York: McGraw-Hill; 1997
- 30 Arbuthnott K, Frank J. Trail making test, part B as a measure of executive control: validation using a set-switching paradigm. J Clin Exp Neuropsychol 2000; 22 (04) 518-528
- 31 Santos GD, Ordonez TN, Costa LA, Souza MAAd, Cardoso NP, Lessa PP. et al. Análise de reprodutibilidade do teste de cálculos do ábaco em pessoas idosas saudáveis. Rev Kairos 2024; 27 (03) 95-114
- 32 Martins BG, Silva WR, Maroco J, Campos JADB. Escala de Depressão, Ansiedade e Estresse: propriedades psicométricas e prevalência das afetividades. J Bras Psiquiatr 2019; 68: 32-41
- 33 Neri AL, Borim FSA, Batistoni SST, Cachioni M, Rabelo DF, Fontes AP, Yassuda MS. Nova validação semântico-cultural e estudo psicométrico da CASP-19 em adultos e idosos brasileiros. Cad Saude Publica 2018; 34 (10) e00181417
- 34 Duarte YAO, Domingues MAR. Validação do Mapa Mínimo de Relações Modificado e Adaptado. In: Duarte YAO, Domingues MAR. Família, rede de suporte social e idosos: instrumentos de avaliação. São Paulo: Blucher; 2020: 183-227
- 35 Studart-Neto A, Moraes NC, Spera RR, Merlin SS, Parmera JB, Jaluul O. et al. Translation, cross-cultural adaptation, and validity of the Brazilian version of the Cognitive Function Instrument. Dement Neuropsychol 2022; 16 (01) 79-88
- 36 Silva TBL, Santos G, Zumkeller MG, Barbosa MEdC, Moreira APB, Ordonez TN. et al. Intervenção cognitiva de longa duração com componentes multifatoriais: um estudo de descrição do Método Supera. Rev Kairos 2021; 24: 117-140
- 37 Brum PS, Yassuda MS. Intervenções cognitivas para idosos. In: Freitas EV, Py L. editors. Tratado de geriatria e gerontologia. 5th ed.. Rio de Janeiro: Guanabara Koogan; 2022: 1266-1275
- 38 Lira JO, Rugene OT, Mello PCH. Desempenho de idosos em testes específicos: efeito de Grupo de Estimulação. Rev Bras Geriatr Gerontol 2011; 14 (02) 209-220 Available from: https://www.scielo.br/j/rbgg/a/Y4ZKK4NXBZhgDcXvhL7fLbR/?format=pdf&lang=pt