Open Access
CC BY 4.0 · Arq Neuropsiquiatr 2025; 83(07): s00451809882
DOI: 10.1055/s-0045-1809882
Original Article

Supera cognitive stimulation study with cognitively-unimpaired older adults: methodology and initial results of a randomized controlled clinical trial

1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
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2   Universidade de São Paulo, Faculdade de Medicina, Departamento de Neurologia, Divisão de Clínica Neurológica, Grupo de Neurologia Cognitiva e do Comportamento, São Paulo SP, Brazil.
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1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.
2   Universidade de São Paulo, Faculdade de Medicina, Departamento de Neurologia, Divisão de Clínica Neurológica, Grupo de Neurologia Cognitiva e do Comportamento, São Paulo SP, Brazil.
› Institutsangaben

Funding The authors declare that the present study was funded by Supera Instituto de Educação.
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Abstract

Scientific investigations have highlighted the benefits of cognitive stimulation for cognitive, psychological, and social aspects in older individuals. However, there is a dearth of long-term, methodologically-rigorous studies. The aim of the present study was to describe the methods and the initial characteristics of the participants in a randomized controlled trial on cognitive stimulation. A total of 578 older individuals accepted invitations to participate in the study. Of these respondents, 362 met the eligibility criteria, and 255 were selected and randomized into the training, active control, and passive control groups. During the baseline stage (T0), 48 participants withdrew, resulting in a final T0 sample of 207 participants. The three groups were similar in terms of cognitive performance and sociodemographic and psychosocial variables, but they differed significantly regarding depressive symptoms, with the training group scoring higher. The methods herein described can help guide future research on cognitive stimulation in older adults.

Authors' Contributions

Conceptualization: TBLS, SMDB, MSY; Data curation: TNO; Investigation: TBLS, TNO, GDS, LAC, APBM, DSB; Methodology: TBLS, APBM, SMDB, MSY; Writing – original draft: TBLS, TNO, GDS, LAC, APBM; Writing – review & editing: TBLS, TNO, GDS, APBM, DSB, MAAS, SAS, SMDB, MSY.


Data Availability Statement

Data is available on demand.


Editor-in-Chief: Hélio A. G. Teive (https://orcid.org/0000-0003-2305-1073).


Associate Editor: Leonardo Cruz de Souza (https://orcid.org/0000-0001-5027-9722).




Publikationsverlauf

Eingereicht: 11. Oktober 2024

Angenommen: 28. April 2025

Artikel online veröffentlicht:
02. Juli 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Thais Bento Lima da Silva, Tiago Nascimento Ordonez, Gabriela dos Santos, Laydiane Alves Costa, Ana Paula Bagli Moreira, Diana dos Santos Bacelar, Maria Antonia Antunes de Souza, Sabrina Aparecida da Silva, Sonia Maria Dozzi Brucki, Monica Sanches Yassuda. Supera cognitive stimulation study with cognitively-unimpaired older adults: methodology and initial results of a randomized controlled clinical trial. Arq Neuropsiquiatr 2025; 83: s00451809882.
DOI: 10.1055/s-0045-1809882