Open Access
CC BY 4.0 · Ibnosina Journal of Medicine and Biomedical Sciences
DOI: 10.1055/s-0045-1809901
Pathology Corner

Allergic Granulomatous Contact Dermatitis: A Reaction to Metal Particles Used in Ear Lobe Piercing

1   Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio, United States
,
1   Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio, United States
2   Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio, United States
› Author Affiliations

Funding and Sponsorship None.
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Abstract

This is an image-based clinical vignette demonstrating a granulomatous reaction to metal particles used in ear lobe piercing in a teenage girl who presented with bilateral lesions on her ear lobes, clinically thought to be keloids. Microscopic examination showed extensive granulomatous inflammation with rare polarizable metal particles seen on H&E-stained sections. The granulomatous inflammation was disproportionately extensive in comparison with the rarity of metal particles triggering the process. The diagnosis of allergic granulomatous contact dermatitis was rendered. This overreaction phenomenon is typical of granulomatous inflammation and this case demonstrates the importance of examination of granulomatous inflammatory lesions under polarized light, especially in the context of negative staining for infectious agents.

Author's Contributions

S.B.K. made the diagnosis, wrote the first draft, and prepared composite photo. S.S. performed literature search and edited manuscript.


Compliance with Ethical Principles

None.




Publication History

Article published online:
24 June 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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