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DOI: 10.1055/s-0045-1810408
The cerebellum and psychiatric disorders: unraveling its role in mental health

Abstract
Several studies describe a strong association between structural and functional abnormalities of the cerebellum and psychiatric disorders. It is possible to find investigations especially in cases of schizophrenia, bipolar disorder, depression, anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD). The involvement of the cerebellum in these conditions is also supported by clinical, functional, and structural imaging studies. The present narrative review aims to discuss and highlight the role of the cerebellum in these disorders, gathering evidence on the possible locations and connections of the affected cerebellar areas and their implications in the cognitive, emotional, and behavioral domains.
Authors' Contributions
Formal analysis: PBN, MWBS, SSOS, RPM, LENF, JLP, OGPB; Writing – original draft: PBN, MWBS, SSOS, RPM, LENF, JLP, OGPB; Writing – review & editing: PBN, MWBS, SSOS, RPM, LENF, JLP, OGPB.
Data Availability Statement
The datasets generated and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Editor-in-Chief: Hélio A. G. Teive (https://orcid.org/0000-0003-2305-1073).
Associate Editor: Antonio Lucio Teixeira (https://orcid.org/0000-0002-9621-5422).
Publikationsverlauf
Eingereicht: 06. März 2025
Angenommen: 19. Mai 2025
Artikel online veröffentlicht:
31. August 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua Rego Freitas, 175, loja 1, República, São Paulo, SP, CEP 01220-010, Brazil
Pedro Braga-Neto, Maria Wanessa Barbosa dos Santos, Stephanie Suzanne de Oliveira Scott, Renato Puppi Munhoz, Luiz Eduardo Novis, José Luiz Pedroso, Orlando Graziani Povoas Barsottini. The cerebellum and psychiatric disorders: unraveling its role in mental health. Arq Neuropsiquiatr 2025; 83: s00451810408.
DOI: 10.1055/s-0045-1810408
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