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CC BY 4.0 · Indian J Med Paediatr Oncol
DOI: 10.1055/s-0045-1810428
Images in Oncology

Broncho-alveolar Lavage Cytology Evidence of Pulmonary Metastasis by Neuroblastoma

Authors

  • Silvia Bozzano

    1   Division of Anatomical Pathology, Department of Integrated Surgical and Diagnostic Sciences, Scuola di Scienze Mediche e Farmaceutiche, Università di Genova, Genoa, Italy

  • Valerio Gaetano Vellone

    2   Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy

  • Barbara Cafferata

    2   Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy

  • Gabriele Gaggero 

    2   Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy

Funding None.
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Introduction

Neuroblastoma (NB) is the most frequent pediatric extracranial solid tumor. It exhibits a high metastatic rate, with approximately 70% of patients presenting with metastasis at diagnosis. While bone and liver are the most common sites, lung involvement occurs in 1.3 to 6.6% of cases.[1] [2] To our knowledge, this report describes the first instance of NB pulmonary metastasis diagnosed using broncho-alveolar lavage (BAL) samples.

Authors' Contributions

S.B.: concept, data acquisition, manuscript preparation, manuscript editing, and manuscript review.


V.G.V.: design, definition of intellectual content, data analysis, statistical analysis, manuscript editing, and manuscript review.


B.C.: clinical studies, experimental studies, data acquisition, and manuscript review.


G.G.: literature search, definition of intellectual content, manuscript preparation, manuscript editing, and manuscript review.


All authors have read and approved the manuscript, meet the requirements for authorship, and believe the manuscript represents honest work.


Patient's Consent

Patient's consent is not required.




Publikationsverlauf

Artikel online veröffentlicht:
28. Juli 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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