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DOI: 10.1055/s-0045-1812046
Thromboangiitis Obliterans Treated with Individualized Homeopathic Medicine: A Case Report
Authors
Abstract
Thromboangiitis obliterans is a nonatherosclerotic, inflammatory disease affecting the small- and medium-sized arteries and veins of the extremities. Its prevalence among patients with peripheral arterial disease varies from 0.5 to 5.6% in Western Europe and 45 to 63% in India. It frequently affects vessels of the upper and lower extremities, where it causes migratory thrombophlebitis and arterial insufficiency. So far, there is no reported study evaluating individualized homeopathic intervention in thromboangiitis obliterans in peer-reviewed journals. The following case study presents a case of small thromboangiitis obliterans presenting with rest pain and ischemic gangrene in the left foot toe. The case was prescribed Carbo Animalis based on local modalities and prominent veins on the affected limb. There was marked improvement in rest pain and full recovery of gangrene, thus avoiding the need for amputation. The modified Naranjo score was +10, which indicated a definite causal attribution. This case study suggests that individualized homeopathic treatment can be helpful in thromboangiitis obliterans with no-option critical limb ischemia. The findings of this case study merit a more rigorous trial to test the action of Carbo Animalis in cases of peripheral arterial diseases.
Keywords
Buerger's disease - Carbo Animalis - individualized homeopathy - ischemic - gangrene - thromboangiitis obliteransPublication History
Article published online:
10 November 2025
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References
- 1 Mitropoulos F, Eforakopoulos F, Kanakis MA, Vassili M, Mastorakou I, Georgiadis M. Diagnostic and therapeutic approach in a patient with Buerger's and coronary artery disease. Case Rep Med 2013; 2013: 974184
- 2 Vijayakumar A, Tiwari R, Kumar Prabhuswamy V. Thromboangiitis obliterans (Buerger's disease)-current practices. Int J Inflamm 2013; 2013: 156905
- 3 Shionoya S. Diagnostic criteria of Buerger's disease. Int J Cardiol 1998; 66 (Suppl. 01) S243-S245 , discussion S247
- 4 Fazeli B, Ligi D, Keramat S, Maniscalco R, Sharebiani H, Mannello F. Recent updates and advances in Winiwarter-Buerger disease (Thromboangiitis obliterans): biomolecular mechanisms, diagnostics and clinical consequences. Diagnostics (Basel) 2021; 11 (10) 1736
- 5 Fang G, Jiang X, Fang Y. et al. Autologous peripheral blood-derived stem cells transplantation for treatment of no-option angiitis-induced critical limb ischemia: 10-year management experience. Stem Cell Res Ther 2020; 11 (01) 458
- 6 Tiwari AK, Yadav AK, Das K, Srivastava BP. Individualized homoeopathic treatment of chronic arterial foot ulcer: a case report. Int J Hum Sci 2022; 6 (04) 182-184
- 7 Ponnam HB, Lamba CD, Oberai P. et al. Calendula mother tincture vs normal saline for ulcer dressing as an add-on to individualized homoeopathic intervention in the management of diabetic foot ulcer: a randomized controlled pilot study. Indian J Res Homoeopathy 2020; 14: 233-241
- 8 Dormandy JA, Rutherford RB. TASC Working Group. Trans Atlantic Inter Society Concensus (TASC). Management of peripheral arterial disease (PAD). TASC Working Group. TransAtlantic Inter-Society Consensus (TASC). J Vasc Surg 2000; 31 (1, Pt 2): S1-S296
- 9 Boger CM. Boger Boenninghausen's Characteristics & Repertory with Corrected & Revised Abbreviations & Word Index. 2nd revised ed.. New Delhi: B. Jain Publishers; 2008
- 10 Kent JT. Repertory of the Homoeopathic Materia Medica and a Word Index. 6th ed.. New Delhi: B. Jain Publishers; 1996
- 11 Hering C. Carbo animalis . In: Raue CG, Knerr CB, Mohr C. eds. The Guiding Symptoms of Our Materia Medica. Vol 3. New Delhi: B. Jain Publishers; 1993. 350.
- 12 van Haselen RA. Homeopathic clinical case reports: development of a supplement (HOM-CASE) to the CARE clinical case reporting guideline. Complement Ther Med 2016; 25: 78-85
- 13 Lamba CD, Gupta VK, van Haselen R. et al. Evaluation of the Modified Naranjo Criteria for assessing causal attribution of clinical outcome to homeopathic intervention as presented in case reports. Homeopathy 2020; 109 (04) 191-197
- 14 Mills Sr JL. Buerger's disease in the 21st century: diagnosis, clinical features, and therapy. Semin Vasc Surg 2003; 16 (03) 179-189
- 15 Igari K, Inoue Y, Iwai T. The epidemiologic and clinical findings of patients with Buerger disease. Ann Vasc Surg 2016; 30: 263-269
- 16 Lee CY, Choi K, Kwon H. et al. Outcomes of endovascular treatment versus bypass surgery for critical limb ischemia in patients with thromboangiitis obliterans. PLoS One 2018; 13 (10) e0205305
- 17 Ponnam HB. Facilitating healing in diabetic foot ulcers using homeopathy in a multi-disciplinary integrative approach: two evidence-based case reports. Homeopathy 2025; 114 (02) 130-137
- 18 Halacheva K, Gulubova MV, Manolova I, Petkov D. Expression of ICAM-1, VCAM-1, E-selectin and TNF-alpha on the endothelium of femoral and iliac arteries in thromboangiitis obliterans. Acta Histochem 2002; 104 (02) 177-184