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CC BY 4.0 · Eur J Dent
DOI: 10.1055/s-0045-1812107
Original Article

Physical and Chemical Properties of All-in-One Root Canal Irrigants: A Laboratory Study

Authors

  • Sonia Gupta 

    1   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India

  • Rajkumar Narkedamalli

    1   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India

  • Krishna Prasad Shetty

    2   Department of Clinical Science, College of Dentistry, Centre of Medical and Bio-allied Health Science Research, Ajman University, Al-Jruf Ajman, United Arab Emirates

  • Nidambur Vasudev Ballal

    1   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
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Abstract

Objective

This ex vivo study aimed to compare the physical and chemical properties of two all-in-one root canal irrigants—Dual Rinse HEDP (DR HEDP) and Triton—with respect to their soft tissue dissolution efficacy, effect on dentin surface roughness, and demineralization potential.

Materials and Methods

Forty extracted human single-rooted teeth were used to evaluate soft tissue dissolution and demineralization, while 40 dentin slices from 20 teeth were used for surface roughness analysis. Irrigants tested included DR HEDP, Triton, NaOCl (positive control) alone, and distilled water (negative control). Soft tissue dissolution was assessed using standardized pulp tissue analogs. Calcium ion release was measured via atomic absorption spectrometry to assess demineralization. Surface roughness was analyzed using atomic force microscopy. Statistical analysis included analysis of variance and Tukey's post hoc tests with significance set at p < 0.05.

Results

DR HEDP and NaOCl alone showed the highest tissue dissolution (36.49 and 35.57%, respectively, p > 0.05), significantly outperforming Triton (29.50%, p < 0.001). Triton exhibited the greatest dentin surface roughness (191.37 nm), significantly higher than DR HEDP (104.25 nm) and NaOCl (101.24 nm) (p < 0.001). Calcium ion release was highest in the Triton group (135.61 mg/L), followed by DR HEDP (49.66 mg/L) and NaOCl (26.06 mg/L), with all intergroup differences being significant (p < 0.001), except between DR HEDP and NaOCl (p > 0.05).

Conclusion

DR HEDP exhibited superior soft tissue dissolution similar to NaOCl, while causing significantly less dentin surface roughness and demineralization than Triton.

Keywords

demineralization - dual rinse HEDP - root canal irrigation - sodium hypochlorite - surface roughness - Triton - tissue dissolution


Publication History

Article published online:
22 October 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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