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DOI: 10.1055/s-0045-1812409
Outcome measurements on physical fitness and function in persons with Myositis – a systematic review
Autoren
Background No consensus exists which outcome measurement instruments (OMIs) are adequate to evaluate physical fitness and function in persons with idiopathic inflammatory myopathy (IIM). Furthermore, the measurement properties of the commonly used OMIs in this population are criticized for being insufficiently described. Therefore, the aim of this systematic review is to provide a comprehensive overview of the measurement properties of OMIs that measure physical fitness and function in adult persons with IIM and to provide recommendations for specific OMIs for research and clinical practice.
Method A systematic literature search in eight databases was conducted. We included full-text articles in English and German evaluating performance-based or clinician-reported OMIs for physical fitness and function in adult persons with IIM. Articles including persons with inclusion body myositis, patient reported outcome measures or laboratory values, studies using OMIs as an outcome measure only, were excluded. Data extraction, risk of bias assessment and evaluation of the measurement properties were performed according to the COSMIN manual. Evidence quality was rated using a modified GRADE approach.
Results We included eleven articles, investigating eleven OMIs with different versions: Twelve different sets of manual muscle testing, four versions of the functional index (FI), three different chair rise tests, three versions of a hand-held dynamometry (HHD), two different arm lift tests, two-minute walk distance, Barré test, Grippit, leg crossing capacity, Mingazzine test, and squatting capacity. Overall ratings of measurement properties were only sufficient for measurement error of HHD (microFET2) total score and for reliability of FI-3 total score, most items of the FI, grippit, and almost all muscle groups measured with different versions of the HHD. The Quality of evidence is low or very low for all measurement properties.
Discussion Based on our results, no specific OMI can be recommended for clinical practice. A substantial number and versions of OMIs, with different measurement protocols were investigated in the included studies. Therefore, we recommend the development and evaluation of core sets, including specific measurement protocols, to assess different constructs of physical fitness and function in persons with IIM.
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Artikel online veröffentlicht:
23. Oktober 2025
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