Introduction

Legs (in evolution) come with a high price: the software to control them… The motors controlling a leg have to alternate between keeping the foot on the ground while it bears and propels the load and taking the load off to make the leg free to move… The controllers also must minimize the wasteful up-and-down motion that is the bane of horseback riders… A still more remarkable feat is controlling the hand…

Steven Pinker, How the Mind Works

References

• 1 Eccles J C. Central cholinergic transmission and its behavioral aspects. Historical introduction.  Fed Proc. 1969;  28 90-94
• 2 Piaget J. The origins of intelligence in children.  New York; International Universities Press 1952
• 3 Sachdev P, Loneragan C. Intravenous benztropine and propranolol challenges in tardive akathisia.  Psychopharmacology (Berl). 1993;  113 119-122