ABSTRACT
Bronchiolitis obliterans with organizing pneumonia (BOOP) is a pathological syndrome
common to a variety of pulmonary inflammatory disorders. It is defined by the presence
of buds of granulation tissue consisting of fibroblasts and collagen within the lumen
of the distal airspaces. BOOP may be secondary to lung injury resulting especially
from infection or drug toxicity or may develop in the context of connective tissue
diseases or after lung or bone marrow transplantation. BOOP may also be idiopathic
(and then preferentially called cryptogenic organizing pneumonia) and then is the
hallmark of a distinct clinicoradiological syndrome of subacute pneumonia, with typical
alveolar patchy and often migratory pulmonary opacities on imaging. Other imaging
presentations consist of diffuse infiltrative opacities or focal pneumonia. Improvement
with corticosteroids is usually spectacular, but relapses are common after stopping
or while reducing treatment.
KEYWORD
Bronchiolitis obliterans organizing pneumonia (BOOP) - organizing pneumonia - interstitial
lung disease
