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Semin Musculoskelet Radiol 2001; 05(2): 113-120
DOI: 10.1055/s-2001-15879
DOI: 10.1055/s-2001-15879
Dialysis-related Amyloidosis
Further Information
Publication History
Publication Date:
31 December 2001 (online)
ABSTRACT
Dialysis-related amyloidosis (DRA) is a well-recognized complication in patients on long-term hemodialysis. It occurs secondary to the deposition of β2-microglobulin, preferentially in the musculoskeletal tissues. Plain radiography demonstrates advanced DRA findings such as bone erosions and cystic lesions, but it is not suitable for the demonstration of earlier changes. Magnetic resonance imaging and ultrasound are sufficient for the detection of amyloid deposition in the periarticular soft tissues and in the evaluation of spinal complications.
KEYWORD
Dialysis - amyloidosis - imaging
REFERENCES
- 1 An overview of regular dialysis treatment in Japan. As of Dec. 31, 1999. Japanese Society for Dialysis Therapy
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- 2 Cobby M J, Adler R S, Swartz R. Dialysis-related amyloid arthropathy: MR findings in four patients. AJR . 1991; 157 1023-1027
- 3 Kurer M H, Baillod R A, Madgwick J C. Musculoskeletal manifestations of amyloidosis. A review of 83 patients on haemodialysis for at least 10 years. J Bone Joint Surg . 1991; 73B 271-276
- 4 Campistol J M, Argiles A. Dialysis-related amyloidosis: visceral involvement and protein constituents. Nephrol Dial Transplant . 1996 (suppl 3); 11 (142-145)
- 5 Danesh F R, Klinkmann J, Yokoo H. Fatal cervical spondyloarthropathy in a hemodialysis patient with systemic deposition of beta 2-microglobulin amyloid. Am J Kidney Dis . 1999; 33 563-566
- 6 Takahashi S, Morita T, Koda Y. Gastrointestinal involvement of dialysis related amyloidosis. Clin Nephrol . 1988; 30 168-171
- 7 Matsuno K, Nakamoto M, Yasunaga C. Dialysis related amyloidosis of the tongue in long-term hemodialysis patients. Kidney Int . 1997; 52 832-838
- 8 Hirshberg A, Kaplan I, Gorsky M. β-2-Microglobulin-associated nodular amyloidosis of the tongue. Int J Oral Maxillofac Surg . 1998; 27 226-228
- 9 Choi S HS, Heller D, Picken M M. Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis. Gastroenterology . 1989; 96 230-234
- 10 Lutz A E, Schneider U, Ehlerding G. Right ventricular cardiac failure and pulmonary hypertension in a long-term dialysis patient-unusual presentation of visceral β2-microglobulin amyloidosis. Nephrol Dial Transplant . 1995; 10 555-558
- 11 Jadoul M, Garbar C, Noel H. Histological prevalence of β2-microglobulin amyloidosis in haemodialysis: a prospective post-mortem study. Kidney Int . 1997; 51 1928-1932
- 12 Koch K M. Dialysis-related amyloidosis-nephron forum. Kidney Int . 1992; 41 1416-1429
- 13 Davison A M. β2-microglobulin (β2m) and amyloidosis: who is at risk?. Nephrol Dial Transplant . 1995 (suppl 10); 10 (48-51)
- 14 van Ypersele de Strihou C, Jadoul M, Malghem J. Effect of dialysis membrane and patient's age on signs of dialysis-related amyloidosis. The Working Party on Dilaysis Amyloidosis. Kidney Int . 1991; 39 1012-1019
- 15 Kuchle C, Fricke H, Held E. High-flux hemodialysis postpones clinical manifestations of dialysis-related arthropathy. Am J Nephrol . 1996; 16 484-488
- 16 Claudon M, Regent D, Gaucher A. MR patterns of dialysis arthropathy. J Comput Assist Tomogr . 1990; 14 968-974
- 17 Jadoul M, Noel H, van Ypersele de Strihou C. β2-M amyloidosis in a patient treated excrusively by CAPD. Am J Kidney Dis . 1990; 15 86-88
- 18 Charra B. Dialysis-related amyloidosis: from raw clinical facts to unresolved questions. Contrib Nephrol . 1995; 112 119-128
- 19 Warren D J, Otieno L S. Carpal tunnel syndrome in patients on intermittent haemodialysis. Postgrad Med J . 1975; 51 450-452
- 20 Assenat H, Calemard E, Charra B. Hemodialyse syndrome du canal carpien et substance amyloide. Nouv Press Med . 1980; 9 1715
- 21 Gejyo F, Yamada T, Odani S. A new form of amyloid protein associated with chronic hemodialysis was identified as β2-microglobulin (β2m). Biochem Res Commun . 1985; 129 701-706
- 22 Gejyo F, Homma N, Suzuki Y. Serum levels of β2-microglobulin as a new form of amyloid protein in patients undergoing long-term hemodialysis. N Engl J Med . 1986; 314 585-586
- 23 Ogawa H, Saito A, Oda O. Detection of novel β2-microglobulin in serum of hemodialysis patients and its amyloidogenic predisposition. Clin Nephrol . 1988; 30 158-163
- 24 Linke R P, Hampl H, Lobeck H. Lysine specific cleavage of β2-microglobulin (β2m) in amyloid deposits associated with hemodialysis. Kidney Int . 1989; 36 375-381
- 25 Capeillere-Blandin C, Delaveau T, Descamps-Latscha B. Structural modifications of human β2-microglobulin treated with oxygen-derived radicals. Biochem J . 1991; 277 175-182
- 26 Miyata T, Oda O, Inagi R. β2-microglobulin modified with advanced glycation end products is a major component of hemodialysis associated amyloidosis. J Clin Invest . 1993; 92 1243-1252
- 27 Miyata T, Inagi R, Iida Y. Involvement of β2-microglobulin modified with advanced glycation end products in the pathogenesis of hemodialysis-associated amyloidosis: induction of human monocyte chemotaxis and macrophage secretion of tumor necrosis factor-α and inteleukin-1. J Clin Invest . 1994; 93 521-528
- 28 Miyata T, Ueda Y, Saito A. `Carbonyl stress' and dialysis-related amyloidosis. Nephrol Dial Transplant . 2000 (suppl 1); 15 (25-28)
- 29 Miyata T, Maeda K. Pathogenesis of dialysis-related amyloidosis. Curr Opin Nephrol Hypertens . 1995; 4 493-497
- 30 Miyata T. New aspects in the pathogenesis of dialysis-related amyloidosis: role of β2-microglobulin modified with advanced glycation end products in bone and joint destruction. Nephrol Dial Transplant . 1996 (suppl 2); 11 (140-143)
- 31 Miyata T, Iida Y, Ueda Y. Monocyte/macrophage response to β2-microglobulin modified with the advanced glycation end products. Kidney Int . 1996; 49 538-550
- 32 Mesgarzadeh M, Triolo J, Schneck C D. Carpal tunnel syndrome. MR imaging diagnosis. Magn Reson Imaging Clin N Am . 1995; 3 249-264
- 33 Monagle K, Dai G, Chu A. Quantitative MR imaging of carpal tunnel syndrome. AJR . 1999; 172 1581-1586
- 34 Buchberger W, Schon G, Strasser K. High-resolution ultrasonography of the carpal tunnel. J Ultrasound Med . 1991; 10 531-537
- 35 Bernageau J, Bardin T, Goutallier D. Magnetic resonance imaging findings in shoulders of hemodialyzed patients. Clin Orthop . 1994; 304 91-96
- 36 Escobedo E M, Hunter J C, Zink-Brody G C, at a l. Magnetic resonance imaging of dialysis-related amyloidosis of the shoulder and hip. Skeletal Radiol . 1996; 25 41-48
- 37 Cardinal E, Buckwalter K A, Braunstein E M. Amyloidosis of the shoulder in patients on chronic haemodialysis: sonographic findings. AJR . 1996; 166 153-156
- 38 Slavotinek J P, Coates P TH, McDonald S P. Shoulder appearances at MR imaging in long-term dialysis recipients. Radiology . 2000; 217 539-543
- 39 Sargent M A. Bone cyst and haemodialysis-related amyloidosis. Clin Radiol . 1989; 40 277-281
- 40 Gierlen J L, van Holsbeeck T M, Hauglustaine D. Growing bone cysts in long-term hemodialysis. Skeletal Radiol . 1990; 19 43-49
- 41 DiRaimondo C R, Casey T T, DiRaimondo C V. Pathologic fractures associated with idiopathic amyloidosis of bone in chronic hemodialysis patients. Nephron . 1986; 43 22-27
- 42 Kokubo T, Takatori Y, Okutsu I. MR demonstration of intraosseous beta-2-microglobulin amyloidosis. J Comput Assist Tomogr . 1990; 14 1030-1032
- 43 Campistol J M, Sole M, Munoz-Gomez J. Pathological fractures in patients who have amyloidosis associated with dialysis. A report of five cases. J Bone Joint Surg Am . 1990; 72 568-574
- 44 Scheumann G F, Holch M, Nerlich M L. Pathological fractures and lytic bone lesion of the femoral neck associated with beta 2-microglobulin amyloid deposition in long-term dialysis patients. Arch Orthop Trauma Surg . 1991; 110 93-97
- 45 Karakida O, Aoki J, Kanno Y. Hemodialysis-related arthropathy: a prospective MR study with SE and GRE sequences. Acta Radiol . 1997; 38 158-164
- 46 Handa S P, Khaliq S U. Swelling of olecranon bursa in uremic patients receiving hemodialysis. Can Med Assoc J . 1978; 118 812-814
- 47 Dantoine M, Castro F, Leblanc M. Popliteal cysts from advanced amyloidosis in long-term haemofiltration/ haemodiafiltration. Nephrol Dial Transplant . 1997; 12 1512-1515
- 48 Jones N, Kjellstrand M. Spontaneous ruptures in patients on chronic dialysis. Am J Kidney Dis . 1996; 28 861-866
- 49 Kuntz D, Naveau B, Bardin T. Destructive spondylarthropathy in hemodialyzed patients. Arthritis Rheum . 1984; 27 369-375
- 50 Sebert J L, Fardellone P, Marie A. Destructive spondylarthropathy in hemodialyzed patients: possible role of amyloidosis. Arthritis Rheum . 1986; 29 301-303
- 51 Sundaram M, Seeling R, Pohl D. Vertebral erosions in patients undergoing maintenance hemodialysis for chronic renal failure. AJR . 1987; 149 323-327
- 52 Kaplan P, Resnick D, Murphey M. Destructive noninfectious spondyloarthropathy in hemodialysis patients: a report of four cases. Radiology . 1987; 162 241-244
- 53 Naidich J B, Mossey R T, McHeffey-Atkinson B. Spondyloarthropathy from long-term hemodialysis. Radiology . 1988; 167 761-764
- 54 Kerr R, Bjorkengren A, Biolocki D K. Destructive spondyloarthropathy in hemodialysis patients. Skeletal Radiol . 1988; 17 176-180
- 55 Choi S HS, Heller D, Picken M M. Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis. Gastroenterology . 1989; 96 230-234
- 56 Maruyama H, Gejyo F, Arakawa M. Clinical studies of destructive spondyloarthropathy in long-term hemodialysis patients. Nephron . 1992; 61 37-44
- 57 Allard J C, Artze M E, Porter G. Fatal destructive cervical spondyloarthropathy in two patients on long-term dialysis. Am J Kidney Dis . 1992; 19 81-85
- 58 Farrell J, Bastani B. β2-microglobulin amyloidosis in chronic dialysis patients: a case report and review of the literature. J Am Soc Nephrol . 1997; 8 509-514
- 59 Paillaud E, Clerc D, Berge E. Pseudotumor of the craniocervical hinge in a patient receiving hemodialysis for 4 years (letter). J Rheumatol . 1993; 20 1634-1635
- 60 Rousselin B, Helenon O, Zingraff J. Pseudotumor of the craniocervical junction during long-term hemodialysis. Arthritis Rheum . 1990; 33 1567-1573
- 61 Chassagne P, Chib M, Said L. Spinal cord compression revealing a destructive arthropathy of the atlanto-occipital joint associated with beta-2 microglobulin amyloidosis in a haemodialyzed patient. Br J Rheumatol . 1992; 31 427-428
- 62 Allain T J, Stevens P E, Bridges L R. Dialysis myelopathy: quadripares is due to extradural amyloid of β2 microglobulin origin. Br Med J . 1988; 296 752-753
- 63 Nokura K, Koga H, Yamamoto H. Dialysis-related spinal canal stenosis: a clinicopathological study on amyloid deposition and its AGE modification. J Neuro Sci . 2000; 178 114-123