Zusammenfassung
Wir berichten über 5 Patientinnen mit einem solid-pseudopapillären Tumor des Pankreas.
Diese Tumoren sind im Kindesalter selten. Mädchen werden deutlich häufiger befallen
als Jungen. Der Malignitätsgrad ist niedrig. Eine Metastasierung, meist in die Leber
oder das Peritoneum, kommt nur selten vor. Die zum Zeitpunkt der Diagnosestellung
oft sehr großen Tumoren sind fast immer vollständig resektabel. Die Prognose gilt
danach als gut. Die Abgrenzung gegen andere Pankreastumoren ist deshalb von Bedeutung.
Abstract
We report on fife female patients with solid pseudopapillary tumors of the pancreas.
The tumors are extremely rare in children. They occur mainly in adolescent and young
adult females. The tumors are neoplasms of low malignancy with infrequent metastases,
for instance, in the liver or the peritoneum. Although the tumors had reached a large
diameter, all of them underwent complete tumor resection. After that the patients
have a very good prognosis. Thus, so it is important to distinguish solid-pseudopapillary
tumors from other tumors of the pancreas.
Schlüsselwörter
Solid-pseudopapillärer Tumor - Pankreas - Papillär-zystischer Tumor - Therapie - Prognose
Key words
Solid-pseuodpapillary tumor - Pancreas - Papillary cystic tumor - Therapy - Prognosis
Literatur
- 1
Bektas H, Werner U, Kaaden S, Philippou S, Klöppel G, Klempnauer J.
Solid-pseudopapillary tumor of the pancreas - rare and frequently misdiagnosed neoplasm.
Langenbeck's Arch Surg.
1999;
384
39-43
- 2
Chao H C, Kong M S, Lin S J, Lou C C, Lin P Y.
Papillary cystic neoplasm of the pancreas in children: report of three cases.
Taiwan Erh Ko I Hsueh Tsa Chih.
2000;
41
101-105
- 3
Carbone A, Ranelletti F O, Rinelli A, et al.
Type II estrogen receptors in the papillary cystic tumor of the pancreas.
Am J Clin Pathol.
1989;
92
572-576
- 4
Chavez M, Perez A, Vargas G, Verona R, Puga R.
A solid epithelial papillary-cystic pancreatic tumor. A report of a clinical case
and review of the literature.
Rev Gastroenterol Peru.
1996;
16
64-71
- 5
Dong P R, Lu D S, Degregario F, Fell S C, Au A, Kadell B M.
Solid and papillary neoplasm of the pancreas: radiological-pathological study of five
cases and review of the literature.
Clin Radiol.
1996;
51
702-705
- 6
Fabbro M A, D'Agostino S, Musi L, Scalabrin U, Dante S.
Cystic-papillary neoplasm of the pancreas: a case report in childhood.
Pediatr Med Chir.
1996;
18
607-610
- 7
Hansson B, Hubens G, Hagendorens M, Deprettere A, Calpaert C, Eyskens E.
Frantz's Tumour of the Pankreas. Presenting as a Post-Traumatic Pancreatic Pseudocyst.
Acta chir belg.
1999;
99
82-84
- 8
Hoorens A, Prenzel K, Nicolas R, Klöppel L and G.
Undifferentiated carcinoma of the pancreas: Analysis of intermediate filament profile
and ki-ras mutations provides evidence of a ductal origin.
J Pathol.
1998;
185
53-60
- 9
Klimstra D S, Wenig B M, Heffess C S.
Solid-pseudopapillary tumor of the pancreas: a typically cystic carcinoma of low malignant
potential.
Semin Diagn Pathol.
2000;
17
66-80
- 10
Mao C, Guvendi M, Domenico D R, Kim K, Thomford N R, Howard J M.
Papillary cystic and solid tumors of the pancreas: a pancreatic embryonic tumor? Studies
of three cases and cumulative review of the world's literature.
Surgery.
1995;
118
821-828
- 11
Matsunou H, Konishi F.
Papillary-cystic neoplasm of the pancreas: a clinicopathologic study concerning the
tumor aging and malignancy of nine cases.
Cancer.
1990;
65
283-291
- 12
Merkle E M, Weber C H, Siech M, Kolokythas O, Tomczak R, Rieber A, Brambs H J.
Papillary cystic and solid tumor of the pancreas.
Z Gastroenterol.
1996;
34
743-746
- 13
Nishihara K, Nagoshi M, Tsuneyoshi M, Yamaguchi K, Hayashi I.
Papillary cystic tumors of the pancreas. Assessment of their malignant potential.
Cancer.
1993;
71
82-92
- 14
Poustchi-Amin M, Leonidas J C, Valderrama E, Shende A, Paley C, Lanzkowsky P, Kutin N.
Papillary-cystic neoplasm of the pancreas.
Pediatr Radiol.
1993;
25
509-511
- 15
Principe A, Lugaresi M L, Lords R C, Golfieri R, D'Errico A, Bicchierri I, Gallo M C,
Polito E, Cavallari A.
Papillary cystic neoplasm of the pancreas: a description of two clinical cases.
Hepatogastroenterology.
1997;
44
1122-1125
- 16
Schmidt-Rohlfing B, Siech M, Mattfeldt T, Schoenberg M H, Beger H G.
Zystische Neoplasien des Pankreas: operative Therapie und Heilungschancen.
Z Gastroenterol.
1998;
36
939-945
- 17
Siech M, Merkle E, Mattfeld T, Widmaier U, Brambs H J, Beger H G.
Solid-pseudopapilläre Tumoren des Pankreas.
Chirurg.
1996;
67
1012-1015
- 18
Snajdauf J, Pycha K, Rygl M, Kocmichova B, Kodet R, Koutecky J, Cumlivska E.
Papillary cystic and solid tumor of the pancreas-surgical therapy with the use of
CUSA, and a review of the pediatric literature.
Eur J Pediatr Surg.
1999;
9
416-419
- 19
Soudack M, Ben-Nun A, Malkin L, Hashmonai M.
Solid and papillary pancreatic neoplasm.
Harefuah.
2000;
138
105-107
- 20
Valdez-Gonzalez R, Molinar L, Ortega-Saldago J A.
Solid and cystic papillary epithelial neoplasms of the pancreas. Images of the tumor
and follow-up.
Gac Med Mex.
1999;
135
333-337
- 21
Wrba F, Chott A, Ludvik B, et al.
Solid and cystic tumor of the pancreas: a hormonal-dependent neoplasm?.
Histopathology.
1988;
12
338-340
- 22
Wunsch L P, Flemming P, Werner U, Gluer S, Burger D.
Diagnosis and treatment of papillary cystic tumor of the pancreas in children.
Eur J Pediatr Surg.
1997;
7
45-47
Dr. med. Sabine Lange
Kinderkrankenhaus der Stadt Köln
Amsterdamer Str. 59
50735 Köln
