ABSTRACT
A Brazilian National Registry was established in 1999 to investigate the incidence
of risk factors for venous thromboembolism (VTE) in hospitalized medical and surgical
patients and to investigate the use of thromboprophylaxis in these populations. A
4-year pilot study confirmed the feasibility and value of a registry project in this
region, showing a dramatic increase in the use of low-molecular-weight heparin (LMWH)
over the study period, associated with a sixfold reduction in the incidence of symptomatic
VTE. Data on more than 27,000 patients from the Brazilian Registry have revealed that
almost 25% of high-risk patients and 45% of those at moderate risk currently receive
no thromboprophylaxis. Among the high-risk patients-in whom general measures alone
are not considered appropriate prophylaxis-42% of patients did not receive pharmacological
prophylaxis with either LMWH or unfractionated heparin. The Brazilian Registry highlights
the need to raise awareness of VTE risk factors and recommended prophylactic regimens
in Latin America.
KEYWORDS
Low-molecular-weight heparin - risk evaluation - surgical patients - thromboprophylaxis
- venous thromboembolism