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DOI: 10.1055/s-2003-45477
© Georg Thieme Verlag Stuttgart · New York
Hepatische Enzephalopathie - Therapie
Hepatic encephalopathy - therapyPublikationsverlauf
eingereicht: 16.10.2003
akzeptiert: 13.11.2003
Publikationsdatum:
15. Dezember 2003 (online)

Die primären therapeutischen Maßnahmen bei hepatischer Enzephalopathie bestehen in der Erkennung und Beseitigung auslösender Faktoren. Die weitere Therapie zielt in erster Linie auf eine Verringerung der Bildung und Resorption toxischer Metabolite im Darm mittels Eiweißrestriktion, Laktulose und oraler Antibiotika. L-Ornithin-L-Aspartat verbessert die Ammoniakentgiftung und die klinische Symptomatik. Bei hepatischer Enzephalopathie im Rahmen eines akuten Leberversagens können hirndrucksenkende Maßnahmen erforderlich sein.
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Prof. Dr. med. Matthias Wettstein
Klinik für Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinikum
Düsseldorf
Moorenstraße 5
40225 Düsseldorf
Telefon: 0211/8116330
Fax: 0211/8118752
eMail: wettstein@med.uni-duesseldorf.de