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Klinische Neurophysiologie 2003; 34(4): 169-175
DOI: 10.1055/s-2003-812578
DOI: 10.1055/s-2003-812578
Originalia
© Georg Thieme Verlag Stuttgart · New York
Funktionelle Magnetresonanztomographie in der Epilepsiediagnostik
Functional MRI in EpilepsyF. G. Woermann1 , M. Mertens1Further Information
Publication History
Publication Date:
09 January 2004 (online)
Zusammenfassung
Die funktionelle Magnetresonanztomographie (fMRT) erlaubt die bildliche Darstellung umschriebener Hirnaktivität. Die dabei auf Hirnschnitte oder die Hirnoberfläche projizierten Aktivitätsmuster bei motorischen, sensorischen oder kognitiven Leistungen können in topografische Beziehungen zu anfallsverursachenden Läsionen gesetzt werden. Inwieweit diese Informationen insbesondere zur präoperativen Abschätzung eines Operationsrisikos klinisch genutzt werden können, ist Gegenstand dieser Übersicht.
Abstract
Functional magnetic resonance imaging (fMRI) allows the visualization of localized brain activation. Localized MR contrast changes associated with sensory-motor or cognitive brain functions are expressed as activation maps and projected onto structural MRI. In patients with epilepsy, fMRI promises to delineate epileptogenic lesions from eloquent cortex. The future clinical use of this method depends highly on its ability to predict postoperative morbidity. Recent fMRI studies on the localization of the motor strip and the lateralization of language and memory are discussed.
Key words
Epilepsy - functional MRI - language - memory
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Dr. med. Friedrich G. Woermann
MRT · Krankenhaus Mara · Epilepsiezentrum Bethel
Maraweg 21
33617 Bielefeld
Email: fgw@mara.de