ABSTRACT
Noninvasive, well-validated clinical tests of autonomic function are available and
are in relatively wide use. These comprise an evaluation of sudomotor, cardiovagal,
and adrenergic functions. These tests are very useful and have resulted in the recognition
of milder degrees of autonomic failure and the presence of orthostatic intolerance
that previously were missed. An extensive normative database and commercial equipment
is available. The main limitations of the tests relate to the fact that they evaluate
mainly the function of target tissues so that the status of autonomic reflexes are
inferred. The tests can be affected by medications. There are more invasive, more
time-consuming, or less validated tests of autonomic function that can directly record
from sympathetic nerve fibers (microneurography) and mesenteric bed to study cerebral
vasoregulation and the status of the veins.
KEYWORDS
QSART - cardiovagal - adrenergic - orthostatic hypotension - tilt