Skull Base 2006; 16(1): 019-024
DOI: 10.1055/s-2005-922096
ORIGINAL ARTICLE

Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Endonasal Endoscopic Duraplasty: Our Experience

Paolo G. Castelnuovo1 , Giovanni Delú1 , Davide Locatelli2 , Giovanni Padoan1 , Francesca De Bernardi1 , Andrea Pistochini1 , Maurizio Bignami1
  • 1Department of Otorhinolaryngology, Azienda Ospedaliera Universitaria, Ospedale di Circolo, Fondazione Macchi, University of Insubria, Varese, Italy
  • 2Department of Neurosurgery, IRCCS Policlinico “S. Matteo,” University of Pavia, Pavia, Italy
Further Information

Publication History

Publication Date:
08 December 2005 (online)

ABSTRACT

Objective: Endoscopic repair of cerebrospinal fluid (CSF) leaks is a recognized technique. We consider our experience and evaluate the outcomes in patients who underwent endoscopic repair of CSF leaks. Methods: A retrospective case note review of 135 patients who underwent anterior cranial repairs of CSF leaks between August 1995 and December 2004 at a tertiary referral center. We describe the technical details and outcomes of care by purely endoscopic procedures. Results: Thirteen patients had combined transcranial and endonasal repairs and 122 patients had their repairs using an endoscopic approach only. There were 64 males and 71 females with ages that ranged from 1 to 75 years (mean age 42 years, median age 44 years). The success rate for first attempt only was 93.4%. Eight of the 122 patients (6.6%) needed a second surgical repair. In one patient a bicoronal approach was necessary while in the other cases a revision endoscopic procedure was appropriate. The period of follow-up ranged from 2 months to 9 years (mean 5 years, median 39 months). Conclusions: Our experience confirmed that endoscopic surgery is an effective and safe method of treatment for most CSF leaks. A variety of different endoscopic techniques allowed CSF leaks to be repaired in almost every site of the anterior skull base with very few exceptions.

REFERENCES

  • 1 El-Banhawy O A, Halaka A N, El-Hafiz Shehab El-Dien A, Ayad H. Subcranial transnasal repair of cerebrospinal fluid rhinorrhea with free autologous grafts by the combined overlay and underlay techniques.  Minim Invasive Neurosurg. 2004;  47 197-202
  • 2 Landeiro J A, Lazaro B, Melo M H. Endonasal endoscopic repair of cerebrospinal fluid rhinorrhea.  Minim Invasive Neurosurg. 2004;  47 173-177
  • 3 Lindstrom D R, Toohill R J, Loehrl T A, Smith T L. Management of cerebrospinal fluid rhinorrhea: the Medical College of Wisconsin experience.  Laryngoscope. 2004;  114 969-974
  • 4 Hegazy H M, Carrau R L, Snyderman C H, Kassam A, Zweig J. Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea: a meta-analysis.  Laryngoscope. 2000;  10 1166-1172
  • 5 Carrau R L, Snyderman C H, Kassam A. The management of cerebrospinal fluid leaks in patients at risk for high-pressure hydrocephalus.  Laryngoscope. 2005;  115 205-212
  • 6 Stammberger H, Greistorfer K, Wolf G, Luxenberger W. Surgical occlusion of cerebrospinal fistulas of anterior skull base using intrathecal sodium fluorescein.  Laryngorhinootologie. 1997;  76 595-607
  • 7 Castelnuovo P, Locatelli D, Mauri S, De Bernardi F. Extended endoscopic approaches to the skull base, anterior cranial base CSF leaks. In: De Divitiis E, Cappabianca P Endoscopic Endonasal Trans-Sphenoidal Surgery. New York, NY; Springer Wien 2003: 137-138
  • 8 Castelnuovo P, Mauri S, Locatelli D, Emanuelli E, Delú G, Di Giulio G. Endoscopic repair of cerebrospinal fluid rhinorrhea: learning from our failures.  Am J Rhinol. 2001;  15 333-342
  • 9 Skedros D G, Cass S P, Hirsch B E, Kelly R H. Beta-2-transferrin assay in the clinical management of cerebrospinal fluid and perilymphatic leaks.  J Otolaryngol. 1993;  22 341-344
  • 10 Meco C, Oberascher G, Arrer E, Moser G, Albegger K. Beta-trace protein test: new guidelines for the reliable diagnosis of cerebrospinal fluid fistula.  Otolaryngol Head Neck Surg. 2003;  129 508-517
  • 11 Wolf G, Greistorfer K, Stammberger H. Der endoskopishe Nechweis von Liquorfisteln mittels der Fluoreszeintechnik [Endoscopic detection of cerebrospinal fluid fistulas with a fluorescence technique. Report of experiences with over 925 cases].  Laryngorhinootologie. 1997;  76 588-594
  • 12 Mokri B, Maher C O, Sencakova D. Spontaneous CSF leaks. Underlying disorder of connective tissue.  Neurology. 2002;  58 814-816

Andrea PistochiniM.D. 

Department of Otorhinolaryngology, Azienda Ospedaliera Universitaria, Ospedale di Circolo

Fondazione Macchi, University of Insubria, Viale Borri 57, 21100 Varese, Italy

Email: andrea.pistochini@virgilio.it

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