Dtsch Med Wochenschr 2006; 131(16): 888-891
DOI: 10.1055/s-2006-939864
Prinzip & Perspektive | Review article
Regenerative Medizin, Hepatologie, Gastroenterologie
© Georg Thieme Verlag KG Stuttgart · New York

Transplantation von Hepatozyten bei Leberversagen

Transplantation of hepatocytes in liver failureM. Ott1 , A. Schneider1 , M. Attaran1 , M. P. Manns1
  • 1Abteilung für Gastroenterologie, Hepatologie und Endokrinologie, Zentrum Innere Medizin, Medizinische Hochschule Hannover
Further Information

Publication History

eingereicht: 16.11.2005

akzeptiert: 16.3.2006

Publication Date:
20 April 2006 (online)

Literatur

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  • 2 Bilir B M, Guinette D, Karrer F. et al . Hepatocyte transplantation in acute liver failure.  Liver Transpl. 2000;  6 32-40
  • 3 Cantz T, Sharma A D, Jochheim-Richter A, Arseniev L, Klein C, Manns M P, Ott M. Reevaluation of bone marrow-derived cells as a source for hepatocyte regeneration.  Cell Transplant. 2004;  13 659-666
  • 4 de Vree J M, Ottenhoff R, Bosma O J, Smith A J, Aten J, Oude Elfering R P. Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis.  Gastroenterology. 2000;  119 1720-1730
  • 5 Fisher R A, Bu D, Thompson M. et al . Defining hepatocellular transplantation in a liver failure patient bridged with hepatocyte infusion.  Transplantation. 2000;  69 303-307
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  • 14 Michel J L, Rabier D, Rambaud C. et al . Intrasplenic transplantation of hepatocytes in spf-ash mice with congenital ornithine transcarbamylase deficiency.  Chirurgie. 1993;  119 666-671
  • 15 Overturf K, Al Dhalimy M, Tanguay R, Brantly M, Ou C N, Finegold M, Grompe M. Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.  Nat Genet. 1996;  12 266-273
  • 16 Ruhnke M, Ungefroren H, Nussler A. et al . Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells.  Gastroenterology. 2005;  128 1774-1786
  • 17 Sandgren E P, Palmiter R D, Heckel J L, Daugherty C C, Brinster R L, Degen J L. Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene.  Cell. 1991;  66 245-256
  • 18 Sharma A D, Cantz T, Richter R. et al . Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver.  Am J Pathol. 2005;  167 555-564
  • 19 Soriano H, Wood R, Kang D. et al . Hepatocellular transplantation in children with fulminant hepatic failure.  Hepatology. 1997;  26 A239
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Prof. Dr. med. Michael Ott

Zentrum Innere Medizin, Abteilung für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule, Hannover

Carl-Neuberg-Straße 1

30625 Hannover

Phone: 0511/5328980

Fax: 0511/5328945

Email: Ott-MHH@GMX.de

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