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Semin Neurol 2006; 26(2): 181-187
DOI: 10.1055/s-2006-939918
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Acute Therapy for Migraine Headaches

Todd D. Rozen1
  • 1Michigan Head-Pain and Neurological Institute, Ann Arbor, Michigan
Further Information

Publication History

Publication Date:
21 April 2006 (online)

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ABSTRACT

The migraine attack is made up of phases, which include the prodrome, aura, and the headache itself. Not every migraineur experiences each phase. Each phase has its own distinct pathogenesis and its own unique acute therapy. The acute therapy for each phase of the migraine attack will be discussed.

KEYWORDS

Migraine - acute therapy - triptans - prodrome - aura

REFERENCES

  • 1 Silberstein S D, Young W B. Migraine aura and prodrome.  Semin Neurol. 1995;  15 175-182
    PubMedGoogle Scholar
  • 2 Waelkens J. Dopamine blockade with domperidone: bridge between prophylactic and abortive treatment of migraine? A dose-finding study.  Cephalalgia. 1984;  4 85-90
    CrossrefPubMedGoogle Scholar
  • 3 Rozen T D. Migraine prodrome: a nose on a face.  Lancet. 2004;  363 517
    CrossrefPubMedGoogle Scholar
  • 4 Silberstein S D, Saper J R, Freitag F G. Migraine: diagnosis and treatment. In: Silberstein SD, Lipton RB, Dalessio DJ Wolff's Headache. Oxford, UK; Oxford University Press 2001: 121-237
    Google Scholar
  • 5 Luciani R, Carter D, Mannix L, Hemphill M, Diamond M, Cady R. Prevention of migraine during prodrome with naratriptan.  Cephalalgia. 2000;  20 122-126
    CrossrefPubMedGoogle Scholar
  • 6 Dalessio DJ Wolff's Headache and Other Head Pain. 4th ed. Oxford; Oxford University Press 1980
    Google Scholar
  • 7 Kupersmith M J, Hass W K, Chase N E. Isoproterenol treatment of visual symptoms in migraine.  Stroke. 1979;  10 299-305
    PubMedGoogle Scholar
  • 8 Goldner J A, Levitt L P. Treatment of complicated migraine with sublingual nifedipine.  Headache. 1987;  27 484-486
    CrossrefPubMedGoogle Scholar
  • 9 Rozen T D. Treatment of a prolonged migraineous aura with intravenous furosemide.  Neurology. 2000;  55 732-733
    PubMedGoogle Scholar
  • 10 Read S J, Smith M I, Benham C D, Hunter A J, Parsons A A. Furosemide inhibits regenerative cortical spreading depression in anaesthetized cats.  Cephalalgia. 1997;  17 826-832
    CrossrefPubMedGoogle Scholar
  • 11 Rothrock J F. Successful treatment of persistent migraine aura with divalproex sodium.  Neurology. 1997;  48 261-262
    PubMedGoogle Scholar
  • 12 Forteza A M, Brozman B, Rabinstein A A, Romano J G, Bradley W G. Acetazolamide for the treatment of migraine with aura in CADASIL.  Neurology. 2001;  57 2144-2145
    PubMedGoogle Scholar
  • 13 Kaube H, Herzog J, Kaufer T, Dichgans M, Diener H C. Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine.  Neurology. 2000;  55 139-141
    CrossrefPubMedGoogle Scholar
  • 14 Rozen T D. Intravenous prochlorperazine combined with intravenous magnesium sulfate can abort a prolonged migrainous aura both during and outside of pregnancy.  Neurology. 2001;  56(suppl 3) A63
    PubMedGoogle Scholar
  • 15 van der Hel W S, van den Bergh W M, Nicolay K, Tulleken K A, Dijkhuizen R M. Suppression of cortical spreading depressions after magnesium treatment in the rat.  Neuroreport. 1998;  9 2179-2182
    PubMedGoogle Scholar
  • 16 Silberstein S D, Saper J R, Freitag F G. Migraine: diagnosis and treatment. In: Silberstein SD, Lipton RB, Dalessio DJ Wolff's Headache. Oxford; Oxford University Press 2001: 121-237
    Google Scholar
  • 17 Cady R K, Lipton R B, Hall C, Stewart W F, O'Quinn S, Gutterman D. Treatment of mild headache in disabled migraine sufferers: results of the Spectrum Study.  Headache. 2000a;  40 792-797
    CrossrefPubMedGoogle Scholar
  • 18 Wang S J, Silberstein S D, Young W B. Droperidol treatment of status migrainosus and refractory migraine.  Headache. 1997;  37 377-382
    CrossrefPubMedGoogle Scholar
  • 19 Gallagher R M. Emergency treatment of intractable migraine.  Headache. 1986;  26 74-75
    CrossrefPubMedGoogle Scholar
  • 20 Saadah H A. Abortive migraine therapy in the office with dexamethasone and prochlorperazine.  Headache. 1994;  34 366-370
    CrossrefPubMedGoogle Scholar
  • 21 Stiller J. Management of acute intractable headaches using IV therapy in an office setting.  Headache. 1992;  32 514-515
    CrossrefPubMedGoogle Scholar
  • 22 Cutrer F M, Mitsikostas D D, Ayata G, Sanchez del Rio M. Attenuation by butalbital of capsaicin-induced c-fos-like immunoreactivity in trigeminal nucleus caudalis.  Headache. 1999;  39 697-704
    PubMedGoogle Scholar
  • 23 Cady R K, Sheftell F, Lipton R B et al.. Effect of early intervention with sumatriptan on migraine pain: retrospective analyses of data from three clinical trials.  Clin Ther. 2000;  22 1035-1048
    CrossrefPubMedGoogle Scholar
  • 24 Burstein R, Cutrer M F, Yarnitsky D. The development of cutaneous allodynia during a migraine attack clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine.  Brain. 2000;  123 1703-1709
    CrossrefPubMedGoogle Scholar
  • 25 Burstein R, Collins B, Jakubowski M. Defeating migraine pain with triptans: a race against the development of cutaneous allodynia.  Ann Neurol. 2004;  55 19-26
    CrossrefPubMedGoogle Scholar

Todd D RozenM.D. 

Michigan Head-Pain and Neurological Institute

3120 Professional Drive, Ann Arbor, MI 48104

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