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Semin Respir Crit Care Med 2006; 27(3): 241-261
DOI: 10.1055/s-2006-945528
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Intensive Management of Hepatic Failure

Mary E. Rinella1 , Arun Sanyal2
  • 1Division of Hepatology, Northwestern University, Chicago, Illinois
  • 2Division of Gastroenterology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia
Further Information

Publication History

Publication Date:
21 June 2006 (online)

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ABSTRACT

A substantial number of patients with liver failure are admitted to the intensive care unit; thus a thorough understanding of the prevention and treatment of complications in such patients is imperative. The management of liver failure is demanding and often involves the combined efforts of many specialists. Critically ill patients with hepatic failure encompass a broad spectrum of disease, ranging from acute liver failure in a patient with no prior history of liver disease, to acute on chronic liver failure. The initial assessment and management of acute liver failure are reviewed with an emphasis on the prevention and treatment of brain edema in the pretransplant setting. The current treatment of complications resulting from decompensated chronic liver disease such as portal hypertensive bleeding; infection, renal failure, and hepatic encephalopathy are then discussed.

KEYWORDS

Liver failure - cerebral edema - portal hypertension - management

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Arun SanyalM.D. 

Division of Gastroenterology, Department of Internal Medicine, Virginia Commonwealth University

MCV Box 980341, Richmond, VA 23298-0341

Email: ajsanyal@hsc.vcu.edu

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