Thorac Cardiovasc Surg 2007; 55(3): 186-189
DOI: 10.1055/s-2006-955874
Original Thoracic

© Georg Thieme Verlag KG Stuttgart · New York

Primary Malignant Fibrous Histiocytoma of the Lung

W. Rzyman1 , K. Jaskiewicz2 , M. Murawski1 , A. Sternau1 , T. Marjanski1 , A. Karmolinski2 , R. Dziadziuszko1
  • 1Department of Thoracic Surgery, Medical University of Gdansk, Gdansk, Poland
  • 2Department of Pathology, Medical University of Gdansk, Gdansk, Poland
Further Information

Publication History

received January 23, 2006

Publication Date:
05 April 2007 (online)

Abstract

Background: Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adults. Its appearance as a primary lung tumor is extremely rare. The cell origin of MFH remains controversial. The treatment of choice for MFH is surgical resection, while the role of chemo- and radiotherapy remains unclear. Methods: A retrospective analysis of 5 patients operated on for primary MFH in the Department of Thoracic Surgery of the Medical University in Gdansk between 1990 and 2000 was performed. Results: Out of approximately 2000 patients operated on for primary malignant lung tumors, five (0.25 %) had MFH. The mean age of the 4 men and 1 woman was 62 years. In all cases radical resection was performed without adjuvant chemo- or radiotherapy. Four patients died within 2 - 7 months after the operation, three of them from distant metastases. The follow-up of one patient is not available. One patient is alive 11 years after the operation. Conclusion: Although surgical resection of MFH is the treatment of choice in MFH, the results are unsatisfactory.

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MD, PhD Witold Rzyman

Department of Thoracic Surgery
Medical University of Gdansk

7 Debinki St.

80211 Gdansk

Poland

Phone: + 48 5 83 49 24 00

Fax: + 48 5 83 49 24 29

Email: wrzyman@amg.gda.pl