The Effects of Growth Hormone Administration In Vivo on Skeletal Muscle Glutamine Metabolism of the Rat

M. Parry-Billings; G. D. Dimitriadis; B. Leighton; D. B. Dunger; E. A. Newsholme

doi:10.1055/s-2007-1002101

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Horm Metab Res 1993; 25(6): 292-293
DOI: 10.1055/s-2007-1002101

Originals Basic

The Effects of Growth Hormone Administration In Vivo on Skeletal Muscle Glutamine Metabolism of the Rat

M. Parry-Billings, G. D. Dimitriadis, B. Leighton, D. B. Dunger¹ , E. A. Newsholme

Department of Biochemistry, University of Oxford, Oxford, United Kingdom
¹Department of Paediatrics, University of Oxford, Oxford, United Kingdom

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Publikationsverlauf

1992

1992

Publikationsdatum:
14. März 2008 (online)

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Summary

Human growth hormone administration to the rat for 3 or 10 days increased the concentrations of glutamine in both skeletal muscle and plasma and the rate of glutamine release was increased from muscle isolated from rats treated with growth hormone for 3 days. Growth hormone may therefore play an important role in the control of glutamine metabolism in muscle.

Key words

Glutamine - Amino Acids - Skeletal Muscle - Growth Hormone