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DOI: 10.1055/s-2007-1003733
© Georg Thieme Verlag, Stuttgart · New York
Transitory Coexistence of Oxytocin and Vasopressin in the Hypothalamo Neurohypophysial System of Parturient Rats
Publikationsverlauf
1991
1991
Publikationsdatum:
14. März 2008 (online)

Summary
We used in situ hybridization and immunocytochemistry to investigate a possible coexistence of vasopressin and oxytocin in hypothalamic neurons of parturient rats. We found that a fraction of magnocellular neurons in the paraventricular and supraoptic nuclei contained immunostaining for both peptides as well as oxytocin and vasopressin mRNA hybridization. Colocalization of immunoreactive vasopressin and oxytocin could be observed in some of the Herring bodies in the median eminence and the posterior lobe. No coexistence of vasopressin and oxytocin was found in pregnant or in lactating animals, indicating that the observed coexistence is transitory, perhaps mediated through changing hormonal conditions peri partum.
Key words
Oxytoxin - Vasopressin - Hypothalamus - Collocalization - Immunocytochemistry - In situ Hybridization - Parturition