Thyroidectomy has a feminizing effect on the carbonic anhydrase isozymes II and III
in male rat liver. These isozymes are known to be sexually differentiated but no treatment
so far administered has produced total feminization and this is also true for thyroidectomy.
Neonatal castration, however, does produce this result, suggesting the possibility
of androgen imprinting for these isozymes during the neonatal period.
Carbonic Anhydrase - Thyroidectomy - Neonatal Imprinting
