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Horm Metab Res 1987; 19(7): 323-324
DOI: 10.1055/s-2007-1011811
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Lack of Effect of Warfarin on L-Thyroxine Metabolism

D. L. Wright, H. E. Carlson, J. M. Hershman1 , E. H. Adelstein
  • Division of Endocrinology, University of Missouri School of Medicine, Medical, Research and Pathology Services, Harry S. Truman Veterans Administration Hospital, Columbia, Missouri, U.S.A.
  • 1Wadsworth Veterans Administration Hospital, Los Angeles, California, U.S.A.
Further Information

Publication History

1985

1986

Publication Date:
14 March 2008 (online)

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Summary

The effect of a single 50 mg dose of warfarin sodium on thyroxine monodeiodination was examined in eight healthy human subjects. There was no evidence that warfarin inhibits 5'-monodeiodination, although such inhibition exists in rats.

Key-Words

Warfarin - L-thyroxine - Monodeiodination

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