Occlusion of the transected bronchus after pneumonectomy was achieved by transthoracic
fibrin sealing in 14 domestic pigs. In 9 additional animals standardized bronchus
stump fistulae could also be closed with fibrin sealant which was applied through
a flexible bronchoscope. An average of 1 ml of fibrin sealant cdntaining 500 units
of thrombin and 3500 units of Aprotinin was necessary to achieve bronchial closure
and to prevent early dissolution of the sealant. Endoscopic closure of a bronchus
fistula by fibrin plug was successfully employed in one clinical case.
Bronchial stump fistula - Pneumonectomy - Endoscopic treatment - Fibrin sealant
