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Horm Metab Res 1984; 16(10): 513-515
DOI: 10.1055/s-2007-1014837
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© Georg Thieme Verlag, Stuttgart · New York

Effects of Somatostatin, Glucagon and Insulin on Glycogen Synthesis in Isolated Rat Hepatocytes

A. J. Bone, S. I. M. Younan, J. M. Conlon
  • Departments of Clinical Biochemistry and Metabolic Medicine and Pharmacological Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
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Publication History

1983

1983

Publication Date:
14 March 2008 (online)

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Summary

The effects of somatostatin on basal and hormonemediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5×10-11 - 1.5×10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5×10-10 M)-induced inhibition of glycogenesis.

Key-Words:

Hepatocytes - Glycogenesis - Stomatostatin - Glucagon - Insulin