Gastric inhibitory polypeptide (GIP) levels during an oral glucose tolerance test
(OGTT) have been determined in eight patients suffering from a single benign beta-cell
adenoma.
GIP hypersecretion and an absent correlation between the insulin: glucose ratio and
plasma GIP concentration have been observed. Our data show that the insulinotropic
effect of GIP is almost abolished in insulinoma patients. This finding may help explain
blood glucose levels and the inappropriate plasma insulin response to oral glucose
often observed in these patients.
GIP
-
Glucose
-
Insulin
-
Insulinoma
