In a canine model small-diameter vascular grafts of knitted Dacron were seeded with
autologous endothelial cells. Four weeks after surgery the grafts were removed. Seeded
grafts showed a pseudo-intima covered by a monolayer, whereas control grafts showed
a cellular lining only at the anastomoses. Graft pretreatment with either fibrin glue
or autologous blood in combination with endothelial cell seeding promoted the neointima
formation.
Vascular prostheses - Endothelial cell seeding - Fibrin glue
