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Int J Sports Med 2007; 28(11): 921-927
DOI: 10.1055/s-2007-964987
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Carbohydrate Effect: Hormone and Oxidative Changes

S. McAnulty1 , L. McAnulty2 , D. Nieman1 , J. Morrow3 , C. Dumke1 , A. Utter1
  • 1Health, Leisure, and Exercise Science, Appalachian State University, Boone, North Carolina, United States
  • 2Family and Consumer Sciences, Appalachian State University, Boone, North Carolina, United States
  • 3Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States
Further Information

Publication History

accepted after revision August 13, 2006

Publication Date:
11 May 2007 (online)

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Abstract

Carbohydrate administration during exercise diminishes stress hormone release, but the relationship of these hormones with oxidative stress has not been examined. Fifteen subjects functioned as their own controls and ingested carbohydrate (6 %) or placebo in a randomized design while cycling for 2.5-h (∼ 75 % V·O2peak). Blood and skeletal muscle samples were collected 30 min pre-exercise, immediately post-exercise, and 12-h post-exercise and analyzed for F2-isoprostanes, ferric reducing ability of plasma, glucose, insulin, cortisol, epinephrine, and muscle glycogen, respectively. Statistical design was a 2 (treatment) × 3 (time) repeated measures analysis of variance. Glucose, insulin, and ferric reducing ability of plasma were significantly higher and F2-isoprostanes, cortisol, and epinephrine significantly lower in carbohydrate versus placebo. The decrease in muscle glycogen was not different. During cycling exercise, oxidative stress appears to be heavily influenced by carbohydrate ingestion and increased stress hormones.

Key words

F2‐isoprostanes - ferric reducing ability of plasma (FRAP) - endurance exercise

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Dr. PhD Steven McAnulty

Health, Leisure, and Exercise Science
Appalachian State University

111 Rivers Street

28608 Boone, NC

United States

Phone: + 1 82 82 62 71 51

Fax: + 1 82 82 62 31 38

Email: mcanltysr@appstate.edu

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