Int J Sports Med 1998; 19(6): 391-400
DOI: 10.1055/s-2007-971935
Physiology and Biochemistry

© Georg Thieme Verlag Stuttgart · New York

Vascular Control of Nutrient Delivery by Flow Redistribution Within Muscle: Implications for Exercise and Post-Exercise Muscle Metabolism

M. G. Clark, S. Rattigan, K. A. Dora, J. M. B. Newman, T. P. D. Eldershaw
  • Division of Biochemistry, Medical School, University of Tasmania, Hobart, Australia
Further Information

Publication History

Publication Date:
09 March 2007 (online)

There is evidence for non-nutritive flow routes within, or associated with, skeletal muscle. Large capillary-like structures are possible candidates. The proportion of flow distributed between nutritive and non-nutritive routes appears to be tightly regulated and can control muscle metabolism and contraction by regulating delivery and product removal. The portion of flow that is carried by the non-nutritive routes at rest affords a flow reserve for amplifying nutrient delivery as muscle begins to work and may determine post-exercise metabolism. Inappropriate signals, however, may diminish nutritive flow to the detriment of muscle performance and post-exercise recovery. New technologies should allow the identification of the non-nutritive routes.