Complete Remission of a Diffuse Pontine Glioma

H. C. Lenard; V. Engelbrecht; G. Janssen; W. Wechsler; Ch. Tautz

doi:10.1055/s-2007-973589

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Neuropediatrics 1998; 29(6): 328-330
DOI: 10.1055/s-2007-973589

Short communications

Complete Remission of a Diffuse Pontine Glioma

H. C. Lenard¹ , V. Engelbrecht³ , G. Janssen¹ , W. Wechsler² , Ch. Tautz⁴

¹Departments of Paediatrics, University of Düsseldorf,
²Departments of Neuropathology, , University of Düsseldorf,
³Departments of Diagnostic Radiology, University of Düsseldorf, and
⁴Department of Paediatrics, Community Hospital, Herdecke, Germany

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Publication History

Publication Date:
12 March 2007 (online)

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Abstract

A patient is described in whom a large diffuse glioma of the pons extending into the midbrain was diagnosed at the age of 2 years. Biopsy showed a fibrillary astrocytoma. After shunting of a hydrocephalus, the clinical symptoms abated without conventional therapy. Repeated MRI studies showed a continuous decrease of the tumour which was no longer visible when the patient was 6.6 years old.

In reviews on spontaneous remissions of oncologic disorders we were unable to find a case of a biologically benign brain stem tumour. There is one isolated report on a similar case, though without histologic documentation.

Key words

Pediatric brain tumours - Pontine glioma

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