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Pharmacopsychiatry 1995; 28(3): 80-83
DOI: 10.1055/s-2007-979595
Original Paper

© Georg Thieme Verlag Stuttgart · New York

Growth-Hormone Response to Clonidine in Panic Disorder Patients in Comparison to Patients with Major Depression and Healthy Controls

H. Gann2 , D. Riemann3 , S. Stoll1 , M. Berger3 , W. E. Müller1
  • 1Departments of Psychiatry and Psychopharmacology, Central Institute of Mental Health, Mannheim, Germany
  • 2Clinical Center Barmen, Wuppertal, Germany
  • 3Psychiatric Clinic, University of Freiburg, Freiburg, Germany
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Publication History

Publication Date:
23 April 2007 (online)

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Abstract

Growth-hormone (GH) responses to the α2-adrenoceptor agonist clonidine were measured in 9 panic disorder patients, in 9 patients fulfilling DSM-III-R criteria for major depressive episode, and in 9 age- and sex-matched controls. GH responses to clonidine were not significantly different between the groups. The data do not agree with the assumption that blunted GH responses to clonidine represent a general feature of panic disorder or major depression.