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Horm Metab Res 1996; 28(6): 289-293
DOI: 10.1055/s-2007-979795
DOI: 10.1055/s-2007-979795
Proceedings
© Georg Thieme Verlag Stuttgart · New York
Genetics of Insulin-Dependent Diabetes; Non-Major Histocompatibility Genes
Further Information
Publication History
Publication Date:
23 April 2007 (online)
Abstract
Recently, the major advances in understanding the genetics of type 1 diabetes have come using the positional cloning approach, both in mouse and human. Construction of congenic mouse strains and, in human, the exploitation of linkage disequilibrium between very closely linked markers and disease-predisposing loci, is enabling fine mapping of these loci.
Key words
Insulin-Dependent Diabetes - Genetics - Non-MHC Genes