Horm Metab Res 1996; 28(6): 294-295
DOI: 10.1055/s-2007-979796

© Georg Thieme Verlag Stuttgart · New York

The Thymus and Central Tolerance

J. Sprent
  • Department of Immunology, The Scripps Research Institute, La Jolla, California, U.S.A.
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Publication History

Publication Date:
23 April 2007 (online)


Thymic selection programs I lymphocytes to tolerate self antigens but respond to foreign antigens. The mechanisms involved in self tolerance induction are discussed.