Fatal Hypertensive Crisis as Presentation of Mitochondrial Complex I Deficiency

Abstract

Complex I deficiency is a frequent defect of the mitochondrial electron transport chain. We report on a 3-year-old boy, who rapidly deteriorated after sudden flushing and collapse. This fatal and unusual case was characterized by widely uncontrollable arterial hypertension. It might indicate that hypertensive crisis could be a potential manifestation of mitochondrial disorders.

Key words

hypertension - mitochondrial electron transport complex I - oxidative phosphorylation

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