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Horm Metab Res 1980; 12(6): 251-256
DOI: 10.1055/s-2007-996260
ORIGINALS

© Georg Thieme Verlag, Stuttgart · New York

Effect of Somatomedin A and Insulin on Cyclic AMP Generation in Isolated Rat Hepatocytes

Rosa Zederman, Carin Grebing, Kerstin Hall, H. Löw
  • Department of Endocrinology, Karolinska Sjukhuset, Stockholm, Sweden
Further Information

Publication History

1978

1979

Publication Date:
14 March 2008 (online)

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Summary

Insulin and somatomedin A were shown to have inhibitory action on glucagon stimulated but not basal cyclic AMP production in isolated rat hepatocytes. The inhibition was dose-dependent and the potency per mol was about 100 fold higher for insulin than for somatomedin A.

Key-Words

Cyclic AMP Level - Rat Hepatocytes - Insulin - Somatomedin A - Lactate/Pyruvate Ratio

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